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Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department

Although influenza may cause death in the geriatric population, the best method for predicting mortality in this population is still unclear. We retrospectively recruited older people (≥65 yr) with influenza visiting the emergency department (ED) of a medical center between January 1, 2010, and Dece...

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Autores principales: Chung, Jui-Yuan, Hsu, Chien-Chin, Chen, Jiann-Hwa, Chen, Wei-Lung, Lin, Hung-Jung, Guo, How-Ran, Huang, Chien-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006148/
https://www.ncbi.nlm.nih.gov/pubmed/29915256
http://dx.doi.org/10.1038/s41598-018-27694-6
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author Chung, Jui-Yuan
Hsu, Chien-Chin
Chen, Jiann-Hwa
Chen, Wei-Lung
Lin, Hung-Jung
Guo, How-Ran
Huang, Chien-Cheng
author_facet Chung, Jui-Yuan
Hsu, Chien-Chin
Chen, Jiann-Hwa
Chen, Wei-Lung
Lin, Hung-Jung
Guo, How-Ran
Huang, Chien-Cheng
author_sort Chung, Jui-Yuan
collection PubMed
description Although influenza may cause death in the geriatric population, the best method for predicting mortality in this population is still unclear. We retrospectively recruited older people (≥65 yr) with influenza visiting the emergency department (ED) of a medical center between January 1, 2010, and December 31, 2015. We performed univariate and multivariate logistic regression to identify independent mortality predictors and then developed a prediction score. Four hundred nine older ED patients with a nearly equal sex ratio were recruited. Five independent mortality predictors were identified: severe coma (Glasgow Coma Scale score ≤8), past histories of cancer and coronary artery disease, elevated C-reactive protein levels (>10 mg/dl), and bandemia (>10% band cells). We divided the patients into three mortality risk and disposition groups: (1) low risk (1.1%; 95% confidence interval [CI], 0.5–3.0%); (2) moderate risk (16.7%; 95% CI, 9.3–28.0%); and (3) high risk (40%; 95% CI, 19.8–64.2%). The area under the receiver operating characteristic curve and the Hosmer-Lemeshow goodness of fit of the GID score were 0.86 and 0.578, respectively. The GID score is an efficient and simple tool for predicting mortality in older ED patients with influenza. Further studies are warranted to validate its use.
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spelling pubmed-60061482018-06-26 Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department Chung, Jui-Yuan Hsu, Chien-Chin Chen, Jiann-Hwa Chen, Wei-Lung Lin, Hung-Jung Guo, How-Ran Huang, Chien-Cheng Sci Rep Article Although influenza may cause death in the geriatric population, the best method for predicting mortality in this population is still unclear. We retrospectively recruited older people (≥65 yr) with influenza visiting the emergency department (ED) of a medical center between January 1, 2010, and December 31, 2015. We performed univariate and multivariate logistic regression to identify independent mortality predictors and then developed a prediction score. Four hundred nine older ED patients with a nearly equal sex ratio were recruited. Five independent mortality predictors were identified: severe coma (Glasgow Coma Scale score ≤8), past histories of cancer and coronary artery disease, elevated C-reactive protein levels (>10 mg/dl), and bandemia (>10% band cells). We divided the patients into three mortality risk and disposition groups: (1) low risk (1.1%; 95% confidence interval [CI], 0.5–3.0%); (2) moderate risk (16.7%; 95% CI, 9.3–28.0%); and (3) high risk (40%; 95% CI, 19.8–64.2%). The area under the receiver operating characteristic curve and the Hosmer-Lemeshow goodness of fit of the GID score were 0.86 and 0.578, respectively. The GID score is an efficient and simple tool for predicting mortality in older ED patients with influenza. Further studies are warranted to validate its use. Nature Publishing Group UK 2018-06-18 /pmc/articles/PMC6006148/ /pubmed/29915256 http://dx.doi.org/10.1038/s41598-018-27694-6 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Chung, Jui-Yuan
Hsu, Chien-Chin
Chen, Jiann-Hwa
Chen, Wei-Lung
Lin, Hung-Jung
Guo, How-Ran
Huang, Chien-Cheng
Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department
title Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department
title_full Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department
title_fullStr Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department
title_full_unstemmed Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department
title_short Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department
title_sort geriatric influenza death (gid) score: a new tool for predicting mortality in older people with influenza in the emergency department
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006148/
https://www.ncbi.nlm.nih.gov/pubmed/29915256
http://dx.doi.org/10.1038/s41598-018-27694-6
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