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CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis

The loss of appropriate cell adhesion normally induces apoptosis via a process termed anoikis. The aim of this study was to investigate the effects of mesenchymal stem cells (MSCs) in the cancer microenvironment on the anoikis resistance and pulmonary metastasis of osteosarcoma (OS) cells, and to ev...

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Detalles Bibliográficos
Autores principales: Du, Lin, Han, Xiu-guo, Tu, Bing, Wang, Min-qi, Qiao, Han, Zhang, Shu-hong, Fan, Qi-ming, Tang, Ting-ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006172/
https://www.ncbi.nlm.nih.gov/pubmed/29915309
http://dx.doi.org/10.1038/s41419-018-0745-0

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