Cargando…
Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data
Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of blood flow or tissue elasticity. Minimal or no need for syst...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006180/ https://www.ncbi.nlm.nih.gov/pubmed/29915367 http://dx.doi.org/10.1038/s41598-018-27552-5 |
_version_ | 1783332786209292288 |
---|---|
author | Kolenderska, Sylwia M. Bräuer, Bastian Vanholsbeeck, Frédérique |
author_facet | Kolenderska, Sylwia M. Bräuer, Bastian Vanholsbeeck, Frédérique |
author_sort | Kolenderska, Sylwia M. |
collection | PubMed |
description | Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of blood flow or tissue elasticity. Minimal or no need for system alterations make functional OCT techniques useful in performing multimodal imaging, where differently contrasted images are produced in a single examination. We propose a method that further extends the current capabilities of OCT and requires no modifications to the system. Our algorithm provides information about the sample’s Group Velocity Dispersion (GVD) and can be easily applied to any OCT dataset acquired with a Fourier domain system. GVD is calculated from the difference in material’s optical thickness measured from two images obtained for different spectral ranges. Instead of using two separate light sources, we propose to apply a filter-based, numerical procedure that synthesizes two spectra from one broadband spectrum. We discuss the limitations of the method and present GVD values for BK7 and sapphire and ocular media: cornea and aqueous humour of a rat eye. Results corroborate previous measurements using two different light sources. |
format | Online Article Text |
id | pubmed-6006180 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-60061802018-06-26 Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data Kolenderska, Sylwia M. Bräuer, Bastian Vanholsbeeck, Frédérique Sci Rep Article Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of blood flow or tissue elasticity. Minimal or no need for system alterations make functional OCT techniques useful in performing multimodal imaging, where differently contrasted images are produced in a single examination. We propose a method that further extends the current capabilities of OCT and requires no modifications to the system. Our algorithm provides information about the sample’s Group Velocity Dispersion (GVD) and can be easily applied to any OCT dataset acquired with a Fourier domain system. GVD is calculated from the difference in material’s optical thickness measured from two images obtained for different spectral ranges. Instead of using two separate light sources, we propose to apply a filter-based, numerical procedure that synthesizes two spectra from one broadband spectrum. We discuss the limitations of the method and present GVD values for BK7 and sapphire and ocular media: cornea and aqueous humour of a rat eye. Results corroborate previous measurements using two different light sources. Nature Publishing Group UK 2018-06-18 /pmc/articles/PMC6006180/ /pubmed/29915367 http://dx.doi.org/10.1038/s41598-018-27552-5 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Kolenderska, Sylwia M. Bräuer, Bastian Vanholsbeeck, Frédérique Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data |
title | Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data |
title_full | Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data |
title_fullStr | Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data |
title_full_unstemmed | Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data |
title_short | Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data |
title_sort | dispersion mapping as a simple postprocessing step for fourier domain optical coherence tomography data |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006180/ https://www.ncbi.nlm.nih.gov/pubmed/29915367 http://dx.doi.org/10.1038/s41598-018-27552-5 |
work_keys_str_mv | AT kolenderskasylwiam dispersionmappingasasimplepostprocessingstepforfourierdomainopticalcoherencetomographydata AT brauerbastian dispersionmappingasasimplepostprocessingstepforfourierdomainopticalcoherencetomographydata AT vanholsbeeckfrederique dispersionmappingasasimplepostprocessingstepforfourierdomainopticalcoherencetomographydata |