The binding of an anti-PD-1 antibody to FcγRΙ has a profound impact on its biological functions

Antibodies targeting PD-1 have been demonstrated durable anti-cancer activity in certain cancer types. However, the anti-PD-1 antibodies are less or not efficacious in many situations, which might be attributed to co-expression of multiple inhibitory receptors or presence of immunosuppressive cells...

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Detalles Bibliográficos
Autores principales: Zhang, Tong, Song, Xiaomin, Xu, Lanlan, Ma, Jie, Zhang, Yanjuan, Gong, Wenfeng, Zhang, Yilu, Zhou, Xiaosui, Wang, Zuobai, Wang, Yali, Shi, Yingdi, Bai, Huichen, Liu, Ning, Yang, Xiaolong, Cui, Xinxin, Cao, Yanping, Liu, Qi, Song, Jing, Li, Yucheng, Tang, Zhiyu, Guo, Mingming, Wang, Lai, Li, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006217/
https://www.ncbi.nlm.nih.gov/pubmed/29687231
http://dx.doi.org/10.1007/s00262-018-2160-x

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