A practical guide for using lithium halocarbenoids in homologation reactions

ABSTRACT: Lithium halocarbenoids are versatile reagents for accomplishing homologation processes. The fast α-elimination they suffer has been considered an important limitation for their extensive use. Herein, we present a series of practical considerations for an effective employment in the homolog...

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Detalles Bibliográficos
Autores principales: Monticelli, Serena, Rui, Marta, Castoldi, Laura, Missere, Giada, Pace, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006224/
https://www.ncbi.nlm.nih.gov/pubmed/29983454
http://dx.doi.org/10.1007/s00706-018-2232-9
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author Monticelli, Serena
Rui, Marta
Castoldi, Laura
Missere, Giada
Pace, Vittorio
author_facet Monticelli, Serena
Rui, Marta
Castoldi, Laura
Missere, Giada
Pace, Vittorio
author_sort Monticelli, Serena
collection PubMed
description ABSTRACT: Lithium halocarbenoids are versatile reagents for accomplishing homologation processes. The fast α-elimination they suffer has been considered an important limitation for their extensive use. Herein, we present a series of practical considerations for an effective employment in the homologation of selected carbon electrophiles. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00706-018-2232-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-60062242018-07-04 A practical guide for using lithium halocarbenoids in homologation reactions Monticelli, Serena Rui, Marta Castoldi, Laura Missere, Giada Pace, Vittorio Monatsh Chem Original Paper ABSTRACT: Lithium halocarbenoids are versatile reagents for accomplishing homologation processes. The fast α-elimination they suffer has been considered an important limitation for their extensive use. Herein, we present a series of practical considerations for an effective employment in the homologation of selected carbon electrophiles. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00706-018-2232-9) contains supplementary material, which is available to authorized users. Springer Vienna 2018-06-11 2018 /pmc/articles/PMC6006224/ /pubmed/29983454 http://dx.doi.org/10.1007/s00706-018-2232-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Monticelli, Serena
Rui, Marta
Castoldi, Laura
Missere, Giada
Pace, Vittorio
A practical guide for using lithium halocarbenoids in homologation reactions
title A practical guide for using lithium halocarbenoids in homologation reactions
title_full A practical guide for using lithium halocarbenoids in homologation reactions
title_fullStr A practical guide for using lithium halocarbenoids in homologation reactions
title_full_unstemmed A practical guide for using lithium halocarbenoids in homologation reactions
title_short A practical guide for using lithium halocarbenoids in homologation reactions
title_sort practical guide for using lithium halocarbenoids in homologation reactions
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006224/
https://www.ncbi.nlm.nih.gov/pubmed/29983454
http://dx.doi.org/10.1007/s00706-018-2232-9
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