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Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas

Sarcomas are malignant tumors derived from mesenchymal tissues and may harbor a subset of cells with cancer stem-like cell (CSC) properties. Platelet-derived growth factor receptors α and β (PDGFR-α/β) play an important role in the maintenance of mesenchymal stem cells. Here we examine the role of P...

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Detalles Bibliográficos
Autores principales:	Chang, Kevin K., Yoon, Changhwan, Yi, Brendan C., Tap, William D., Simon, M. Celeste, Yoon, Sam S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006341/ https://www.ncbi.nlm.nih.gov/pubmed/29915281 http://dx.doi.org/10.1038/s41389-018-0059-1

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