Cargando…
Purifying and positive selection in the evolution of stop codons
Modes of evolution of stop codons in protein-coding genes, especially the conservation of UAA, have been debated for many years. We reconstructed the evolution of stop codons in 40 groups of closely related prokaryotic and eukaryotic genomes. The results indicate that the UAA codons are maintained b...
Autores principales: | Belinky, Frida, Babenko, Vladimir N., Rogozin, Igor B., Koonin, Eugene V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006363/ https://www.ncbi.nlm.nih.gov/pubmed/29915293 http://dx.doi.org/10.1038/s41598-018-27570-3 |
Ejemplares similares
-
Selection on start codons in prokaryotes and potential compensatory nucleotide substitutions
por: Belinky, Frida, et al.
Publicado: (2017) -
Crossing fitness valleys via double substitutions within codons
por: Belinky, Frida, et al.
Publicado: (2019) -
No evidence for widespread positive selection on double substitutions within codons in primates and yeasts
por: Belinky, Frida, et al.
Publicado: (2022) -
Analysis of Stop Codons within Prokaryotic Protein-Coding Genes Suggests Frequent Readthrough Events
por: Belinky, Frida, et al.
Publicado: (2021) -
Mutational hotspots in the TP53 gene and, possibly, other tumor suppressors evolve by positive selection
por: Glazko, Galina V, et al.
Publicado: (2006)