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MicroRNA-378 is involved in hedgehog-driven epithelial-to-mesenchymal transition in hepatocytes of regenerating liver

Healthy livers have a remarkable regenerative capacity for reconstructing functional hepatic parenchyma after 70% partial hepatectomy (PH). Hepatocytes, usually quiescent in normal healthy livers, proliferate to compensate for hepatic loss after PH. However, the mechanism of hepatocyte involvement i...

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Detalles Bibliográficos
Autores principales: Kim, Jieun, Hyun, Jeongeun, Wang, Sihyung, Lee, Chanbin, Jung, Youngmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006434/
https://www.ncbi.nlm.nih.gov/pubmed/29915286
http://dx.doi.org/10.1038/s41419-018-0762-z