Construction of an anti-programmed death-ligand 1 chimeric antigen receptor and determination of its antitumor function with transduced cells

A chimeric antigen receptor (CAR) is a type of fusion protein that comprises an antigen-recognition domain and signaling domains. In the present study, a programmed death-ligand 1 (PD-L1)-specific CAR, comprised of a single-chain variable fragment (scFv) derived from a monoclonal antibody, co-stimul...

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Detalles Bibliográficos
Autores principales: Xie, Jiasen, Zhou, Zishan, Jiao, Shunchang, Li, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006445/
https://www.ncbi.nlm.nih.gov/pubmed/29928397
http://dx.doi.org/10.3892/ol.2018.8617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006445/
https://www.ncbi.nlm.nih.gov/pubmed/29928397
http://dx.doi.org/10.3892/ol.2018.8617

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