Cargando…

Asymmetric synthesis of allylic amines via hydroamination of allenes with benzophenone imine

Rhodium-catalyzed highly regio- and enantioselective hydroamination of allenes is reported. Exclusive branched selectivities and excellent enantioselectivities were achieved applying a rhodium(i)/Josiphos catalyst. This method permits the practical synthesis of valuable α-chiral allylic amines using...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Kun, Wang, Yu-Hsuan, Khakyzadeh, Vahid, Breit, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006468/ https://www.ncbi.nlm.nih.gov/pubmed/29997823 http://dx.doi.org/10.1039/c5sc04984a

Ejemplares similares

Enantioselective construction of C-chiral allylic sulfilimines via the iridium-catalyzed allylic amination with S,S-diphenylsulfilimine: asymmetric synthesis of primary allylic amines
por: Grange, Rebecca L., et al.
Publicado: (2015)

Asymmetric synthesis of N-allylic indoles via regio- and enantioselective allylation of aryl hydrazines
por: Xu, Kun, et al.
Publicado: (2015)

Pd-catalyzed asymmetric allylic alkylations via C–H activation of N-allyl imines with glycinates
por: Trost, Barry M., et al.
Publicado: (2017)

The Pd-catalysed asymmetric allylic alkylation reactions of sulfamidate imines
por: Pham, Quoc Hoang, et al.
Publicado: (2021)

Rhodium-catalyzed asymmetric intramolecular hydroarylation of allenes: access to functionalized benzocycles
por: Berthold, Dino, et al.
Publicado: (2019)

Asymmetric hydroalkylation of alkynes and allenes with imidazolidinone derivatives: α-alkenylation of α-amino acids
por: Panahi, Farhad, et al.
Publicado: (2021)

Gold-catalyzed intermolecular hydroamination of allenes with sulfonamides
por: Zhang, Chen, et al.
Publicado: (2013)

Enantioselective carbene insertion into the N–H bond of benzophenone imine
por: Yang, Jian, et al.
Publicado: (2019)

Rhodium-catalyzed asymmetric hydroamination and hydroindolation of keto-vinylidenecyclopropanes
por: Yang, Song, et al.
Publicado: (2018)

Enantioselective and site-specific copper-catalyzed reductive allyl–allyl cross-coupling of allenes
por: Xu, Guoxing, et al.
Publicado: (2018)

Enantioselective copper catalysed, direct functionalisation of allenes via allyl copper intermediates
por: Pulis, Alexander P., et al.
Publicado: (2017)

Computational investigations of the binding mechanism of novel benzophenone imine inhibitors for the treatment of breast cancer
por: Shtaiwi, Amneh, et al.
Publicado: (2019)

Stereodivergent synthesis via iridium-catalyzed asymmetric double allylic alkylation of cyanoacetate
por: Shen, Chong, et al.
Publicado: (2021)

Hydroamination of Aromatic Alkynes to Imines Catalyzed by Pd(II)–Anthraphos Complexes
por: Erken, Christina, et al.
Publicado: (2020)

Practical synthesis of allylic amines via nickel-catalysed multicomponent coupling of alkenes, aldehydes, and amides
por: Xiao, Wei-Guo, et al.
Publicado: (2023)

Asymmetric synthesis of multifunctional aryl allyl ethers by nucleophilic catalysis
por: Zhao, Shuai, et al.
Publicado: (2019)

Enantioselective synthesis of gem-disubstituted N-Boc diazaheterocycles via decarboxylative asymmetric allylic alkylation
por: Sun, Alexander W., et al.
Publicado: (2018)

Reductive aminations by imine reductases: from milligrams to tons
por: Gilio, Amelia K., et al.
Publicado: (2022)

Allylic C(sp(3))–H alkylation via synergistic organo- and photoredox catalyzed radical addition to imines
por: Jia, Jiaqi, et al.
Publicado: (2020)

Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines
por: Poh, Jian‐Siang, et al.
Publicado: (2017)

A metal π-Lewis base activation model for Pd-catalyzed hydroamination of amines and 1,3-dienes
por: Yan, Xiao, et al.
Publicado: (2023)

Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination
por: Niu, Dawen, et al.
Publicado: (2015)

Phosphinoindenyl and phosphazidoindenyl complexes of lanthanum and samarium: synthesis, characterisation, and hydroamination catalysis
por: Steiner, Matthias R., et al.
Publicado: (2021)

Titanium-mediated reductive cross-coupling reactions of imines with terminal alkynes: An efficient route for the synthesis of stereodefined allylic amines
por: Mao, Kebin, et al.
Publicado: (2013)

From imine to amine: an unexpected left turn. Cis-β iron(ii) PNNP′ precatalysts for the asymmetric transfer hydrogenation of acetophenone
por: Demmans, Karl Z., et al.
Publicado: (2017)

An approach to new chiral bicyclic imines and amines via Horner–Wadsworth–Emmons reaction
por: Iwanejko, Jakub, et al.
Publicado: (2020)

Enantioselective nickel-catalyzed arylative and alkenylative intramolecular 1,2-allylations of tethered allene–ketones
por: Di Sanza, Riccardo, et al.
Publicado: (2020)

Intramolecular Csp(3)–H/C–C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines
por: Wen, Xiaojin, et al.
Publicado: (2020)

Copper-Catalyzed Enantioselective Borylative Allyl–Allyl Coupling of Allenes and Allylic gem-Dichlorides
por: Piñeiro-Suárez, Martín, et al.
Publicado: (2023)

Catalytic Formal Hydroamination of Allylic Alcohols Using Manganese PNP‐Pincer Complexes
por: Duarte de Almeida, Leandro, et al.
Publicado: (2021)

Copper‐Catalyzed Borylative Cross‐Coupling of Allenes and Imines: Selective Three‐Component Assembly of Branched Homoallyl Amines
por: Rae, James, et al.
Publicado: (2015)

Jumping in the Chiral Pool: Asymmetric Hydroaminations with Early Metals
por: Notz, Sebastian, et al.
Publicado: (2023)

Radical transformations for allene synthesis
por: Li, Yajun, et al.
Publicado: (2022)

Continuous-flow synthesis of 3,5-disubstituted pyrazoles via sequential alkyne homocoupling and Cope-type hydroamination
por: Ötvös, Sándor B., et al.
Publicado: (2019)

Direct synthesis of amides and imines by dehydrogenative homo or cross-coupling of amines and alcohols catalyzed by Cu-MOF
por: Anbardan, Soheil Zamani, et al.
Publicado: (2021)

A redox-enabled strategy for intramolecular hydroamination
por: Allen, Meredith A., et al.
Publicado: (2022)

Asymmetric synthesis of 1,2-fluorohydrin: iridium catalyzed hydrogenation of fluorinated allylic alcohol
por: Ponra, Sudipta, et al.
Publicado: (2020)

γ-Selective C(sp(3))–H amination via controlled migratory hydroamination
por: Lee, Changseok, et al.
Publicado: (2021)

Synthesis of 4-substituted ethers of benzophenone and their antileishmanial activities
por: Ahad, Faiza, et al.
Publicado: (2018)

Desymmetrization of unactivated bis-alkenes via chiral Brønsted acid-catalysed hydroamination
por: Yu, Zhang-Long, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sk8qflrlhdrp03luk86mqvhknc