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KDM1A microenvironment, its oncogenic potential, and therapeutic significance

The lysine-specific histone demethylase 1A (KDM1A) was the first demethylase to challenge the concept of the irreversible nature of methylation marks. KDM1A, containing a flavin adenine dinucleotide (FAD)-dependent amine oxidase domain, demethylates histone 3 lysine 4 and histone 3 lysine 9 (H3K4me1...

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Detalles Bibliográficos
Autores principales: Ismail, Tayaba, Lee, Hyun-Kyung, Kim, Chowon, Kwon, Taejoon, Park, Tae Joo, Lee, Hyun-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006565/
https://www.ncbi.nlm.nih.gov/pubmed/29921310
http://dx.doi.org/10.1186/s13072-018-0203-3