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Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
Retroperitoneal liposarcoma is a rare type of cancer. Relapse after surgery is frequent, and relapsing tumors tend to be more aggressive and less differentiated each episode, worsening the prognosis. This report describes the case of a 42-year-old female diagnosed with retroperitoneal liposarcoma af...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006640/ https://www.ncbi.nlm.nih.gov/pubmed/29928214 http://dx.doi.org/10.1159/000489393 |
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author | Da Silva, Filipe Rocha Lima, Alan Vitor Jerônimo Albuquerque, Erick Willian Rocha Pereira Moreira-Silva, Carlos Augusto De Oliveira, Nicole Maués Flexa Ohana, Jorge Alberto Langbeck Carvalho, Luís Eduardo Werneck |
author_facet | Da Silva, Filipe Rocha Lima, Alan Vitor Jerônimo Albuquerque, Erick Willian Rocha Pereira Moreira-Silva, Carlos Augusto De Oliveira, Nicole Maués Flexa Ohana, Jorge Alberto Langbeck Carvalho, Luís Eduardo Werneck |
author_sort | Da Silva, Filipe Rocha |
collection | PubMed |
description | Retroperitoneal liposarcoma is a rare type of cancer. Relapse after surgery is frequent, and relapsing tumors tend to be more aggressive and less differentiated each episode, worsening the prognosis. This report describes the case of a 42-year-old female diagnosed with retroperitoneal liposarcoma after complete tumor resection. At the 3-month follow-up, another expansive lipomatous mass in the retroperitoneal area almost the same size as the previous one was detected. The patient underwent a new surgery, followed by first-line treatment with a gemcitabine- and docetaxel-based regimen for 8 cycles. Finally, the patient achieved complete tumor remission confirmed by CT after the end of the treatment proposed. Although recurrence is a well-known characteristic of this neoplasia, no other case with such a vast expansion of a new tumor shortly after complete resection was found in the literature. |
format | Online Article Text |
id | pubmed-6006640 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-60066402018-06-20 Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report Da Silva, Filipe Rocha Lima, Alan Vitor Jerônimo Albuquerque, Erick Willian Rocha Pereira Moreira-Silva, Carlos Augusto De Oliveira, Nicole Maués Flexa Ohana, Jorge Alberto Langbeck Carvalho, Luís Eduardo Werneck Case Rep Oncol Case Report Retroperitoneal liposarcoma is a rare type of cancer. Relapse after surgery is frequent, and relapsing tumors tend to be more aggressive and less differentiated each episode, worsening the prognosis. This report describes the case of a 42-year-old female diagnosed with retroperitoneal liposarcoma after complete tumor resection. At the 3-month follow-up, another expansive lipomatous mass in the retroperitoneal area almost the same size as the previous one was detected. The patient underwent a new surgery, followed by first-line treatment with a gemcitabine- and docetaxel-based regimen for 8 cycles. Finally, the patient achieved complete tumor remission confirmed by CT after the end of the treatment proposed. Although recurrence is a well-known characteristic of this neoplasia, no other case with such a vast expansion of a new tumor shortly after complete resection was found in the literature. S. Karger AG 2018-05-31 /pmc/articles/PMC6006640/ /pubmed/29928214 http://dx.doi.org/10.1159/000489393 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Da Silva, Filipe Rocha Lima, Alan Vitor Jerônimo Albuquerque, Erick Willian Rocha Pereira Moreira-Silva, Carlos Augusto De Oliveira, Nicole Maués Flexa Ohana, Jorge Alberto Langbeck Carvalho, Luís Eduardo Werneck Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report |
title | Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report |
title_full | Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report |
title_fullStr | Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report |
title_full_unstemmed | Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report |
title_short | Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report |
title_sort | complete remission of recurrent retroperitoneal liposarcoma after the administration of gemcitabine and docetaxel as first-line adjuvant chemotherapy: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006640/ https://www.ncbi.nlm.nih.gov/pubmed/29928214 http://dx.doi.org/10.1159/000489393 |
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