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Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report

Retroperitoneal liposarcoma is a rare type of cancer. Relapse after surgery is frequent, and relapsing tumors tend to be more aggressive and less differentiated each episode, worsening the prognosis. This report describes the case of a 42-year-old female diagnosed with retroperitoneal liposarcoma af...

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Autores principales: Da Silva, Filipe Rocha, Lima, Alan Vitor Jerônimo, Albuquerque, Erick Willian Rocha Pereira, Moreira-Silva, Carlos Augusto, De Oliveira, Nicole Maués Flexa, Ohana, Jorge Alberto Langbeck, Carvalho, Luís Eduardo Werneck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006640/
https://www.ncbi.nlm.nih.gov/pubmed/29928214
http://dx.doi.org/10.1159/000489393
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author Da Silva, Filipe Rocha
Lima, Alan Vitor Jerônimo
Albuquerque, Erick Willian Rocha Pereira
Moreira-Silva, Carlos Augusto
De Oliveira, Nicole Maués Flexa
Ohana, Jorge Alberto Langbeck
Carvalho, Luís Eduardo Werneck
author_facet Da Silva, Filipe Rocha
Lima, Alan Vitor Jerônimo
Albuquerque, Erick Willian Rocha Pereira
Moreira-Silva, Carlos Augusto
De Oliveira, Nicole Maués Flexa
Ohana, Jorge Alberto Langbeck
Carvalho, Luís Eduardo Werneck
author_sort Da Silva, Filipe Rocha
collection PubMed
description Retroperitoneal liposarcoma is a rare type of cancer. Relapse after surgery is frequent, and relapsing tumors tend to be more aggressive and less differentiated each episode, worsening the prognosis. This report describes the case of a 42-year-old female diagnosed with retroperitoneal liposarcoma after complete tumor resection. At the 3-month follow-up, another expansive lipomatous mass in the retroperitoneal area almost the same size as the previous one was detected. The patient underwent a new surgery, followed by first-line treatment with a gemcitabine- and docetaxel-based regimen for 8 cycles. Finally, the patient achieved complete tumor remission confirmed by CT after the end of the treatment proposed. Although recurrence is a well-known characteristic of this neoplasia, no other case with such a vast expansion of a new tumor shortly after complete resection was found in the literature.
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spelling pubmed-60066402018-06-20 Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report Da Silva, Filipe Rocha Lima, Alan Vitor Jerônimo Albuquerque, Erick Willian Rocha Pereira Moreira-Silva, Carlos Augusto De Oliveira, Nicole Maués Flexa Ohana, Jorge Alberto Langbeck Carvalho, Luís Eduardo Werneck Case Rep Oncol Case Report Retroperitoneal liposarcoma is a rare type of cancer. Relapse after surgery is frequent, and relapsing tumors tend to be more aggressive and less differentiated each episode, worsening the prognosis. This report describes the case of a 42-year-old female diagnosed with retroperitoneal liposarcoma after complete tumor resection. At the 3-month follow-up, another expansive lipomatous mass in the retroperitoneal area almost the same size as the previous one was detected. The patient underwent a new surgery, followed by first-line treatment with a gemcitabine- and docetaxel-based regimen for 8 cycles. Finally, the patient achieved complete tumor remission confirmed by CT after the end of the treatment proposed. Although recurrence is a well-known characteristic of this neoplasia, no other case with such a vast expansion of a new tumor shortly after complete resection was found in the literature. S. Karger AG 2018-05-31 /pmc/articles/PMC6006640/ /pubmed/29928214 http://dx.doi.org/10.1159/000489393 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Da Silva, Filipe Rocha
Lima, Alan Vitor Jerônimo
Albuquerque, Erick Willian Rocha Pereira
Moreira-Silva, Carlos Augusto
De Oliveira, Nicole Maués Flexa
Ohana, Jorge Alberto Langbeck
Carvalho, Luís Eduardo Werneck
Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
title Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
title_full Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
title_fullStr Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
title_full_unstemmed Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
title_short Complete Remission of Recurrent Retroperitoneal Liposarcoma after the Administration of Gemcitabine and Docetaxel as First-Line Adjuvant Chemotherapy: A Case Report
title_sort complete remission of recurrent retroperitoneal liposarcoma after the administration of gemcitabine and docetaxel as first-line adjuvant chemotherapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006640/
https://www.ncbi.nlm.nih.gov/pubmed/29928214
http://dx.doi.org/10.1159/000489393
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