Cargando…

Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass

[Figure: see text]

Detalles Bibliográficos
Autores principales:	Ahn, Bumsoo, Pharaoh, Gavin, Premkumar, Pavithra, Huseman, Kendra, Ranjit, Rojina, Kinter, Michael, Szweda, Luke, Kiss, Tamas, Fulop, Gabor, Tarantini, Stefano, Csiszar, Anna, Ungvari, Zoltan, Van Remmen, Holly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006677/ https://www.ncbi.nlm.nih.gov/pubmed/29673700 http://dx.doi.org/10.1016/j.redox.2018.04.004

Ejemplares similares

Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness
por: Qaisar, Rizwan, et al.
Publicado: (2018)

Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation
por: Pharaoh, Gavin, et al.
Publicado: (2021)

Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching
por: Ahn, Bumsoo, et al.
Publicado: (2019)

Acylated Ghrelin Receptor Agonist HM01 Decreases Lean Body and Muscle Mass, but Unacylated Ghrelin Protects against Redox-Dependent Sarcopenia
por: Ranjit, Rojina, et al.
Publicado: (2022)

Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia
por: Ahn, Bumsoo, et al.
Publicado: (2022)

Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice
por: Pharaoh, Gavin, et al.
Publicado: (2019)

Restoration of Sarcoplasmic Reticulum Ca(2+) ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice
por: Qaisar, Rizwan, et al.
Publicado: (2020)

Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function
por: Pharaoh, Gavin, et al.
Publicado: (2019)

Oxidative stress‐induced dysregulation of excitation–contraction coupling contributes to muscle weakness
por: Qaisar, Rizwan, et al.
Publicado: (2018)

Myocardial Hypertrophy and Compensatory Increase in Systolic Function in a Mouse Model of Oxidative Stress
por: Varshney, Rohan, et al.
Publicado: (2021)

Cancer cachexia in a mouse model of oxidative stress
por: Brown, Jacob L., et al.
Publicado: (2020)

Using MRI to measure in vivo free radical production and perfusion dynamics in a mouse model of elevated oxidative stress and neurogenic atrophy
por: Ahn, Bumsoo, et al.
Publicado: (2019)

Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype
por: Tarantini, Stefano, et al.
Publicado: (2017)

Targeting cPLA(2) derived lipid hydroperoxides as a potential intervention for sarcopenia
por: Pharaoh, Gavin, et al.
Publicado: (2020)

Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
por: Logan, Sreemathi, et al.
Publicado: (2018)

Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia
por: Xu, Hongyang, et al.
Publicado: (2021)

From Geroscience Discoveries to Public Health Practice: Shifting the Paradigm towards Healthy Ageing
por: Csiszar, A, et al.
Publicado: (2023)

Fusogenic Liposomes Deliver Resveratrol to Brain Microcirculation and Improve Neurovascular Coupling in Aged Mice
por: Toth, Adam Nyul, et al.
Publicado: (2020)

Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation
por: Ungvari, Zoltan, et al.
Publicado: (2019)

A Quantitative Proteomic Profile of the Nrf2-Mediated Antioxidant Response of Macrophages to Oxidized LDL Determined by Multiplexed Selected Reaction Monitoring
por: Kinter, Caroline S., et al.
Publicado: (2012)

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
por: Tarantini, Stefano, et al.
Publicado: (2019)

Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection
por: Toth, Peter, et al.
Publicado: (2015)

Impact of aging and oxidative stress on specific components of excitation contraction coupling in regulating force generation
por: Xu, Hongyang, et al.
Publicado: (2022)

Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
por: Tarantini, Stefano, et al.
Publicado: (2018)

Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission
por: Valencak, Teresa G., et al.
Publicado: (2021)

Companion animals likely do not spread COVID-19 but may get infected themselves
por: Csiszar, Anna, et al.
Publicado: (2020)

Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain
por: Ahire, Chetan, et al.
Publicado: (2023)

Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPR(MT) and increased resistance to oxidative stress in primary cultures of fibroblasts
por: Pharaoh, Gavin, et al.
Publicado: (2016)

The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment
por: Ungvari, Anna, et al.
Publicado: (2023)

Hypertension-induced cognitive impairment: from pathophysiology to public health
por: Ungvari, Zoltan, et al.
Publicado: (2021)

NMN Rescues Endothelial Function and Neurovascular Coupling, Improving Cognitive Function in Aged Mice
por: Tarantini, Stefano, et al.
Publicado: (2020)

Enhanced cardiac fatty acid utilization induced by high dietary fat: a potential regulatory role for mitochondrial aconitase
por: Fernandes, Jolyn, et al.
Publicado: (2012)

Rapid Inhibition of Pyruvate Dehydrogenase: An Initiating Event in High Dietary Fat-Induced Loss of Metabolic Flexibility in the Heart
por: Crewe, Clair, et al.
Publicado: (2013)

Demonstration Of Age-Related Increase In Blood-Brain Barrier Permeability By Longitudinal Intravital Microscopy
por: Toth, Adam Nyul, et al.
Publicado: (2021)

Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer’s Disease
por: Xu, Hongyang, et al.
Publicado: (2022)

Diaphragm Atrophy and Contractile Dysfunction in a Murine Model of Pulmonary Hypertension
por: Ahn, Bumsoo, et al.
Publicado: (2013)

Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice
por: Deepa, Sathyaseelan S., et al.
Publicado: (2018)

Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures
por: Pandics, Tamas, et al.
Publicado: (2023)

Psychological resilience and competence: key promoters of successful aging and flourishing in late life
por: Zábó, Virág, et al.
Publicado: (2023)

Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice
por: Brown, Jacob L., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2nk12olkjufjchlhla883qguj0