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Immunotherapy to improve cognition and reduce pathological species in an Alzheimer’s disease mouse model

BACKGROUND: Alzheimer’s disease (AD) is characterized by physiologically endogenous proteins amyloid beta (Aβ) and tau undergoing a conformational change and accumulating as soluble oligomers and insoluble aggregates. Tau and Aβ soluble oligomers, which contain extensive β-sheet secondary structure,...

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Detalles Bibliográficos
Autores principales:	Herline, Krystal, Prelli, Frances, Mehta, Pankaj, MacMurray, Claire, Goñi, Fernando, Wisniewski, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006698/ https://www.ncbi.nlm.nih.gov/pubmed/29914551 http://dx.doi.org/10.1186/s13195-018-0384-9

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