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Cooperation of PD-1 and LAG-3 in the exhaustion of CD4(+) and CD8(+) T cells during bovine leukemia virus infection

Bovine leukemia virus (BLV) is a retrovirus that infects B cells in cattle and causes bovine leukosis after a long latent period. Progressive exhaustion of T cell functions is considered to facilitate disease progression of BLV infection. Programmed death-1 (PD-1) and lymphocyte activation gene-3 (L...

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Detalles Bibliográficos
Autores principales:	Okagawa, Tomohiro, Konnai, Satoru, Nishimori, Asami, Maekawa, Naoya, Goto, Shinya, Ikebuchi, Ryoyo, Kohara, Junko, Suzuki, Yasuhiko, Yamada, Shinji, Kato, Yukinari, Murata, Shiro, Ohashi, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006750/ https://www.ncbi.nlm.nih.gov/pubmed/29914540 http://dx.doi.org/10.1186/s13567-018-0543-9

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