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Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties

BACKGROUND: Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using preclinical models of castrate-resistant prostate cancer mediated in part by 5′-adenosine monophosphate-activated protein kinase (AMPK), a master energy sensor of the cell. Clinically, treatment with Zyflamend...

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Detalles Bibliográficos
Autores principales: MacDonald, Amber F., Bettaieb, Ahmed, Donohoe, Dallas R., Alani, Dina S., Han, Anna, Zhao, Yi, Whelan, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006779/
https://www.ncbi.nlm.nih.gov/pubmed/29914450
http://dx.doi.org/10.1186/s12906-018-2255-0