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Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties
BACKGROUND: Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using preclinical models of castrate-resistant prostate cancer mediated in part by 5′-adenosine monophosphate-activated protein kinase (AMPK), a master energy sensor of the cell. Clinically, treatment with Zyflamend...
Autores principales: | MacDonald, Amber F., Bettaieb, Ahmed, Donohoe, Dallas R., Alani, Dina S., Han, Anna, Zhao, Yi, Whelan, Jay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006779/ https://www.ncbi.nlm.nih.gov/pubmed/29914450 http://dx.doi.org/10.1186/s12906-018-2255-0 |
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