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A phase IIa proof-of-concept, placebo-controlled, randomized, double-blind, crossover, single-dose clinical trial of a new class of bronchodilator for acute asthma
BACKGROUND: This study evaluates a novel bronchodilator, S1226, for its efficacy in reversing allergen-induced bronchoconstriction in subjects with mild, allergic asthma. S1226 is a new class of bronchodilator that is an aerosol/vapor/gas mixture combining pharmacological and biophysical principles...
Autores principales: | Swystun, Veronica, Green, Francis H. Y., Dennis, John H., Rampakakis, Emmanouil, Lalli, Gurkeet, Fadayomi, Morenike, Chiu, Andrea, Shrestha, Grishma, El Shahat, Sharif Galal, Nelson, David Evan, El Mays, Tamer Y., Pieron, Cora A., Leigh, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006836/ https://www.ncbi.nlm.nih.gov/pubmed/29914544 http://dx.doi.org/10.1186/s13063-018-2720-6 |
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