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Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols

A highly efficient, gold-catalyzed intramolecular dearomatization reaction of naphthols via 5-endo-dig cyclization is described. This facile and direct approach furnishes spirocarbocycles in excellent yields under mild conditions.

Detalles Bibliográficos
Autores principales: Wu, Wen-Ting, Xu, Ren-Qi, Zhang, Liming, You, Shu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006865/
https://www.ncbi.nlm.nih.gov/pubmed/29997837
http://dx.doi.org/10.1039/c5sc04130a
Descripción
Sumario:A highly efficient, gold-catalyzed intramolecular dearomatization reaction of naphthols via 5-endo-dig cyclization is described. This facile and direct approach furnishes spirocarbocycles in excellent yields under mild conditions.