How to address the challenges of evaluating treatment benefits-risks in rare diseases? A convergent mixed methods approach applied within a Merkel cell carcinoma phase 2 clinical trial

BACKGROUND: Demonstrating treatment benefits within clinical trials in the context of rare diseases is often methodologically and practically challenging. Mixed methods research offers an approach to overcome these challenges by combining quantitative and qualitative data, thus providing a better un...

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Detalles Bibliográficos
Autores principales: Bharmal, Murtuza, Guillemin, Isabelle, Marrel, Alexia, Arnould, Benoit, Lambert, Jérémy, Hennessy, Meliessa, Fofana, Fatoumata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006962/
https://www.ncbi.nlm.nih.gov/pubmed/29914528
http://dx.doi.org/10.1186/s13023-018-0835-1

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