Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux

Little is known about the iron efflux from the pancreas, but it is likely that multicopper ferroxidases (MCFs) are involved in this process. We thus used hephaestin (Heph) and ceruloplasmin (Cp) single-knockout mice and Heph/Cp double-knockout mice to investigate the roles of MCFs in pancreatic iron...

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Detalles Bibliográficos
Autores principales: Chen, Min, Zheng, Jiashuo, Liu, Guohao, Xu, En, Wang, Junzhuo, Fuqua, Brie K., Vulpe, Chris D., Anderson, Gregory J., Chen, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007082/
https://www.ncbi.nlm.nih.gov/pubmed/29883959
http://dx.doi.org/10.1016/j.redox.2018.05.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007082/
https://www.ncbi.nlm.nih.gov/pubmed/29883959
http://dx.doi.org/10.1016/j.redox.2018.05.013

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