Cargando…
Sustainable data and metadata management at the BD2K-LINCS Data Coordination and Integration Center
The NIH-funded LINCS Consortium is creating an extensive reference library of cell-based perturbation response signatures and sophisticated informatics tools incorporating a large number of perturbagens, model systems, and assays. To date, more than 350 datasets have been generated including transcr...
Autores principales: | Stathias, Vasileios, Koleti, Amar, Vidović, Dušica, Cooper, Daniel J., Jagodnik, Kathleen M., Terryn, Raymond, Forlin, Michele, Chung, Caty, Torre, Denis, Ayad, Nagi, Medvedovic, Mario, Ma'ayan, Avi, Pillai, Ajay, Schürer, Stephan C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007090/ https://www.ncbi.nlm.nih.gov/pubmed/29917015 http://dx.doi.org/10.1038/sdata.2018.117 |
Ejemplares similares
-
LINCS Data Portal 2.0: next generation access point for perturbation-response signatures
por: Stathias, Vasileios, et al.
Publicado: (2020) -
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
por: Koleti, Amar, et al.
Publicado: (2018) -
SigCom LINCS: data and metadata search engine for a million gene expression signatures
por: Evangelista, John Erol, et al.
Publicado: (2022) -
Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends characterizing systems-level drug action
por: Vidović, Dušica, et al.
Publicado: (2014) -
Connecting omics signatures and revealing biological mechanisms with iLINCS
por: Pilarczyk, Marcin, et al.
Publicado: (2022)