Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling

Almost invariably, humans become ill during primary infections with malaria parasites which is a pathology associated with oxidative stress and perturbations in metabolism. Importantly, repetitive exposure to Plasmodium results in asymptomatic infections, which is a condition defined as clinical tol...

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Detalles Bibliográficos
Autores principales: Gardinassi, Luiz G., Arévalo-Herrera, Myriam, Herrera, Sócrates, Cordy, Regina J., Tran, ViLinh, Smith, Matthew R., Johnson, Michelle S., Chacko, Balu, Liu, Ken H., Darley-Usmar, Victor M., Go, Young-Mi, Jones, Dean P., Galinski, Mary R., Li, Shuzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007173/
https://www.ncbi.nlm.nih.gov/pubmed/29698924
http://dx.doi.org/10.1016/j.redox.2018.04.011

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