Cargando…

Comparison of NSAIDs activity in COX-2 expressing and non-expressing 2D and 3D pancreatic cancer cell cultures

PURPOSE: In this study, we evaluated the anticancer activity of non-steroidal anti-inflammatory drugs (NSAIDs) in BxPC-3 and MIA PaCa-2 pancreatic cancer cell cultures. METHODS: To test the effect of compounds on the viability of cells, the MTT assay was used. The activity of NSAIDs in 3D cell cultu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Čeponytė, Ugnė, Paškevičiūtė, Miglė, Petrikaitė, Vilma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007190/ https://www.ncbi.nlm.nih.gov/pubmed/29942156 http://dx.doi.org/10.2147/CMAR.S163747

Ejemplares similares

Differences of statin activity in 2D and 3D pancreatic cancer cell cultures
por: Paškevičiūtė, Miglė, et al.
Publicado: (2017)

Proton Pump Inhibitors Modulate Transport Of Doxorubicin And Its Liposomal Form Into 2D And 3D Breast Cancer Cell Cultures
por: Paškevičiūtė, Miglė, et al.
Publicado: (2019)

Evaluation of low-intensity pulsed ultrasound on doxorubicin delivery in 2D and 3D cancer cell cultures
por: Paškevičiūtė, Miglė, et al.
Publicado: (2020)

Exploration of Benzenesulfonamide-Bearing Imidazole Derivatives Activity in Triple-Negative Breast Cancer and Melanoma 2D and 3D Cell Cultures
por: Balandis, Benas, et al.
Publicado: (2021)

Comparative Study of Lipophilic Statin Activity in 2D and 3D in vitro Models of Human Breast Cancer Cell Lines MDA-MB-231 and MCF-7
por: Bytautaite, Meda, et al.
Publicado: (2020)

Relative Value of the NSAIDs, Including COX-2 Inhibitors and Meloxicam
por: Curtiss, Frederic R.
Publicado: (2006)

Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures
por: Daunys, Simonas, et al.
Publicado: (2019)

Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia
por: Skaraitė, Ieva, et al.
Publicado: (2023)

COX2 genetic variation, NSAIDs, and advanced prostate cancer risk
por: Cheng, I, et al.
Publicado: (2007)

Novel N-Substituted Amino Acid Hydrazone-Isatin Derivatives: Synthesis, Antioxidant Activity, and Anticancer Activity in 2D and 3D Models In Vitro
por: Tumosienė, Ingrida, et al.
Publicado: (2021)

Prevention of NSAID-related upper gastrointestinal toxicity: a meta-analysis of traditional NSAIDs with gastroprotection and COX-2 inhibitors
por: Rostom, Alaa, et al.
Publicado: (2009)

Pancreatic Stellate Cells (PSCs) express Cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs
por: Yoshida, Seiya, et al.
Publicado: (2005)

Expression and Molecular Regulation of the Cox2 Gene in Gastroenteropancreatic Neuroendocrine Tumors and Antiproliferation of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
por: Gao, Feng, et al.
Publicado: (2018)

Selective COX-2 inhibitors, NSAIDs and cardiovascular events – is celecoxib the safest choice?
por: Howes, Laurence Guy
Publicado: (2007)

Cardiovascular and gastrointestinal effects of COX-2 inhibitors and NSAIDs: achieving a balance
por: Borer, Jeffrey S, et al.
Publicado: (2005)

An observational study of the discrediting of COX-2 NSAIDs in Australia: Vioxx or class effect?
por: Parkinson, Lynne, et al.
Publicado: (2011)

COX-2: Where are we in 2003? - Distinction from NSAIDs becoming blurred
por: Day, Richard
Publicado: (2003)

3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs
por: Barbosa, Mélanie A. G., et al.
Publicado: (2021)

Practical approaches to minimizing gastrointestinal and cardiovascular safety concerns with COX-2 inhibitors and NSAIDs
por: Scheiman, James M, et al.
Publicado: (2005)

Selective COX-2 inhibitor continues to be a safe alternative in patients with nonselective NSAIDs hypersensitivity
por: Thalappil, Sherin, et al.
Publicado: (2022)

The importance of provocation tests with COX2 inhibitors on patients with a history of cross-hypersensitivity to non-steroidal anti-inflammatory (NSAIDs)
por: Gonçalves, Tania Tavares
Publicado: (2015)

COX-2 inhibitory NSAID-induced multiple stenosis in the small intestine diagnosed by double-balloon endoscopy
por: Ueno, Yasuaki, et al.
Publicado: (2016)

New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation
por: Bokhtia, Riham M., et al.
Publicado: (2023)

Aspirin Ameliorates Pancreatic Inflammation and Fibrosis by Inhibiting COX-2 Expression in Experimental Chronic Pancreatitis
por: Xu, Xiao-Fan, et al.
Publicado: (2022)

Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues
por: Li, Li, et al.
Publicado: (2022)

The Effect of 1,2,4-Triazole-3-thiol Derivatives Bearing Hydrazone Moiety on Cancer Cell Migration and Growth of Melanoma, Breast, and Pancreatic Cancer Spheroids
por: Šermukšnytė, Aida, et al.
Publicado: (2022)

Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity — A Critical Update
por: Laube, Markus, et al.
Publicado: (2013)

NSAIDs, are they dangerous for pancreatic surgery?
por: Lee, Ji-Hyun
Publicado: (2022)

Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer
por: Bu, Xianmin, et al.
Publicado: (2011)

Gastrointestinal Bleeding Rates Among Managed Care Patients Newly Started on COX-2 Inhibitors or Nonselective NSAIDs
por: Stockl, Karen, et al.
Publicado: (2005)

Comparison of the Expression of Hepatic Genes by Human Wharton’s Jelly Mesenchymal Stem Cells Cultured in 2D and 3D Collagen Culture Systems
por: Khodabandeh, Zahra, et al.
Publicado: (2016)

Efficacy and tolerability of naproxen/esomeprazole magnesium tablets compared with non-specific NSAIDs and COX-2 inhibitors: a systematic review and network analyses
por: Datto, Catherine, et al.
Publicado: (2013)

The Effect of Beta Adrenoreceptor Blockers on Viability and Cell Colony Formation of Non-Small Cell Lung Cancer Cell Lines A549 and H1299
por: Sidorova, Marina, et al.
Publicado: (2022)

MLK3 is a novel target of dehydroglyasperin D for the reduction in UVB-induced COX-2 expression in vitro and in vivo
por: Jung, Sung Keun, et al.
Publicado: (2015)

Expression of cyclooxygenase-2 (COX-2) in pituitary tumours
por: Sokołowski, Grzegorz, et al.
Publicado: (2012)

Analysis of the Activity and Expression of Cyclooxygenases COX1 and COX2 in THP-1 Monocytes and Macrophages Cultured with Biodentine(TM) Silicate Cement
por: Barczak, Katarzyna, et al.
Publicado: (2020)

Immunohistochemical Expression of COX-2 in Thyroid Nodules
por: Kim, Sang Jin, et al.
Publicado: (2003)

Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions
por: Kolodkin-Gal, Dror, et al.
Publicado: (2022)

Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis
por: Latimer, Nicholas, et al.
Publicado: (2009)

Network Meta-Analysis Comparing Relatively Selective COX-2 Inhibitors Versus Coxibs for the Prevention of NSAID-Induced Gastrointestinal Injury
por: Yang, Man, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h3j1ulr2kthpe4ui5nbh2p03nl