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Expression of 4E-BP1 and phospho-4E-BP1 correlates with the prognosis of patients with clear cell renal carcinoma

BACKGROUND: Eukaryotic translation initiation factor 4E (eIF4E) is a key regulator of protein synthesis. Changes in eIF4E activity disproportionally affect the translation of a subset of oncogenic mRNAs in some cancers. MATERIALS AND METHODS: We have assessed the expression levels of vascular endoth...

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Detalles Bibliográficos
Autores principales: Li, Feng, Wang, Qingshui, Xiong, Xiaoxue, Wang, Chenyi, Liu, Xiaohua, Liao, Ziqiang, Li, Ke, Xie, Bifeng, Lin, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007205/
https://www.ncbi.nlm.nih.gov/pubmed/29942157
http://dx.doi.org/10.2147/CMAR.S158547