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MPD: a pathogen genome and metagenome database

Advances in high-throughput sequencing have led to unprecedented growth in the amount of available genome sequencing data, especially for bacterial genomes, which has been accompanied by a challenge for the storage and management of such huge datasets. To facilitate bacterial research and related st...

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Autores principales: Zhang, Tingting, Miao, Jiaojiao, Han, Na, Qiang, Yujun, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007212/
https://www.ncbi.nlm.nih.gov/pubmed/29917040
http://dx.doi.org/10.1093/database/bay055
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author Zhang, Tingting
Miao, Jiaojiao
Han, Na
Qiang, Yujun
Zhang, Wen
author_facet Zhang, Tingting
Miao, Jiaojiao
Han, Na
Qiang, Yujun
Zhang, Wen
author_sort Zhang, Tingting
collection PubMed
description Advances in high-throughput sequencing have led to unprecedented growth in the amount of available genome sequencing data, especially for bacterial genomes, which has been accompanied by a challenge for the storage and management of such huge datasets. To facilitate bacterial research and related studies, we have developed the Mypathogen database (MPD), which provides access to users for searching, downloading, storing and sharing bacterial genomics data. The MPD represents the first pathogenic database for microbial genomes and metagenomes, and currently covers pathogenic microbial genomes (6604 genera, 11 071 species, 41 906 strains) and metagenomic data from host, air, water and other sources (28 816 samples). The MPD also functions as a management system for statistical and storage data that can be used by different organizations, thereby facilitating data sharing among different organizations and research groups. A user-friendly local client tool is provided to maintain the steady transmission of big sequencing data. The MPD is a useful tool for analysis and management in genomic research, especially for clinical Centers for Disease Control and epidemiological studies, and is expected to contribute to advancing knowledge on pathogenic bacteria genomes and metagenomes. Database URL: http://data.mypathogen.org
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spelling pubmed-60072122018-06-25 MPD: a pathogen genome and metagenome database Zhang, Tingting Miao, Jiaojiao Han, Na Qiang, Yujun Zhang, Wen Database (Oxford) Database Tool Advances in high-throughput sequencing have led to unprecedented growth in the amount of available genome sequencing data, especially for bacterial genomes, which has been accompanied by a challenge for the storage and management of such huge datasets. To facilitate bacterial research and related studies, we have developed the Mypathogen database (MPD), which provides access to users for searching, downloading, storing and sharing bacterial genomics data. The MPD represents the first pathogenic database for microbial genomes and metagenomes, and currently covers pathogenic microbial genomes (6604 genera, 11 071 species, 41 906 strains) and metagenomic data from host, air, water and other sources (28 816 samples). The MPD also functions as a management system for statistical and storage data that can be used by different organizations, thereby facilitating data sharing among different organizations and research groups. A user-friendly local client tool is provided to maintain the steady transmission of big sequencing data. The MPD is a useful tool for analysis and management in genomic research, especially for clinical Centers for Disease Control and epidemiological studies, and is expected to contribute to advancing knowledge on pathogenic bacteria genomes and metagenomes. Database URL: http://data.mypathogen.org Oxford University Press 2018-06-14 /pmc/articles/PMC6007212/ /pubmed/29917040 http://dx.doi.org/10.1093/database/bay055 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Tool
Zhang, Tingting
Miao, Jiaojiao
Han, Na
Qiang, Yujun
Zhang, Wen
MPD: a pathogen genome and metagenome database
title MPD: a pathogen genome and metagenome database
title_full MPD: a pathogen genome and metagenome database
title_fullStr MPD: a pathogen genome and metagenome database
title_full_unstemmed MPD: a pathogen genome and metagenome database
title_short MPD: a pathogen genome and metagenome database
title_sort mpd: a pathogen genome and metagenome database
topic Database Tool
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007212/
https://www.ncbi.nlm.nih.gov/pubmed/29917040
http://dx.doi.org/10.1093/database/bay055
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