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A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
It is necessary for molecular breeders to overcome the difficulties in applying abundant genomic information to crop breeding. Candidate orthologs would be discovered more efficiently in less-studied crops if the information gained from studies of related crops were used. We developed a comparative...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007222/ https://www.ncbi.nlm.nih.gov/pubmed/29873704 http://dx.doi.org/10.1093/database/bay047 |
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author | Choe, Junkyoung Kim, Ji-Eun Lee, Bong-Woo Lee, Jeong Hee Nam, Moon Park, Youn-Il Jo, Sung-Hwan |
author_facet | Choe, Junkyoung Kim, Ji-Eun Lee, Bong-Woo Lee, Jeong Hee Nam, Moon Park, Youn-Il Jo, Sung-Hwan |
author_sort | Choe, Junkyoung |
collection | PubMed |
description | It is necessary for molecular breeders to overcome the difficulties in applying abundant genomic information to crop breeding. Candidate orthologs would be discovered more efficiently in less-studied crops if the information gained from studies of related crops were used. We developed a comparative analysis tool and web-based genome viewer to identify orthologous genes based synteny as well as sequence similarity between tomato, pepper and potato. The tool has a step-by-step interface with multiple viewing levels to support the easy and accurate exploration of functional orthologs. Furthermore, it provides access to single nucleotide-polymorphism markers from the massive genetic resource pool in order to accelerate the development of molecular markers for candidate orthologs in the Solanaceae. This tool provides a bridge between genome data and breeding by supporting effective marker development, data utilization and communication. Database URL: http://tgsol.seeders.co.kr/scomp/ |
format | Online Article Text |
id | pubmed-6007222 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60072222018-06-25 A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae Choe, Junkyoung Kim, Ji-Eun Lee, Bong-Woo Lee, Jeong Hee Nam, Moon Park, Youn-Il Jo, Sung-Hwan Database (Oxford) Database Tool It is necessary for molecular breeders to overcome the difficulties in applying abundant genomic information to crop breeding. Candidate orthologs would be discovered more efficiently in less-studied crops if the information gained from studies of related crops were used. We developed a comparative analysis tool and web-based genome viewer to identify orthologous genes based synteny as well as sequence similarity between tomato, pepper and potato. The tool has a step-by-step interface with multiple viewing levels to support the easy and accurate exploration of functional orthologs. Furthermore, it provides access to single nucleotide-polymorphism markers from the massive genetic resource pool in order to accelerate the development of molecular markers for candidate orthologs in the Solanaceae. This tool provides a bridge between genome data and breeding by supporting effective marker development, data utilization and communication. Database URL: http://tgsol.seeders.co.kr/scomp/ Oxford University Press 2018-06-03 /pmc/articles/PMC6007222/ /pubmed/29873704 http://dx.doi.org/10.1093/database/bay047 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Tool Choe, Junkyoung Kim, Ji-Eun Lee, Bong-Woo Lee, Jeong Hee Nam, Moon Park, Youn-Il Jo, Sung-Hwan A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae |
title | A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae |
title_full | A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae |
title_fullStr | A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae |
title_full_unstemmed | A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae |
title_short | A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae |
title_sort | comparative synteny analysis tool for target-gene snp marker discovery: connecting genomics data to breeding in solanaceae |
topic | Database Tool |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007222/ https://www.ncbi.nlm.nih.gov/pubmed/29873704 http://dx.doi.org/10.1093/database/bay047 |
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