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A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae

It is necessary for molecular breeders to overcome the difficulties in applying abundant genomic information to crop breeding. Candidate orthologs would be discovered more efficiently in less-studied crops if the information gained from studies of related crops were used. We developed a comparative...

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Autores principales: Choe, Junkyoung, Kim, Ji-Eun, Lee, Bong-Woo, Lee, Jeong Hee, Nam, Moon, Park, Youn-Il, Jo, Sung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007222/
https://www.ncbi.nlm.nih.gov/pubmed/29873704
http://dx.doi.org/10.1093/database/bay047
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author Choe, Junkyoung
Kim, Ji-Eun
Lee, Bong-Woo
Lee, Jeong Hee
Nam, Moon
Park, Youn-Il
Jo, Sung-Hwan
author_facet Choe, Junkyoung
Kim, Ji-Eun
Lee, Bong-Woo
Lee, Jeong Hee
Nam, Moon
Park, Youn-Il
Jo, Sung-Hwan
author_sort Choe, Junkyoung
collection PubMed
description It is necessary for molecular breeders to overcome the difficulties in applying abundant genomic information to crop breeding. Candidate orthologs would be discovered more efficiently in less-studied crops if the information gained from studies of related crops were used. We developed a comparative analysis tool and web-based genome viewer to identify orthologous genes based synteny as well as sequence similarity between tomato, pepper and potato. The tool has a step-by-step interface with multiple viewing levels to support the easy and accurate exploration of functional orthologs. Furthermore, it provides access to single nucleotide-polymorphism markers from the massive genetic resource pool in order to accelerate the development of molecular markers for candidate orthologs in the Solanaceae. This tool provides a bridge between genome data and breeding by supporting effective marker development, data utilization and communication. Database URL: http://tgsol.seeders.co.kr/scomp/
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spelling pubmed-60072222018-06-25 A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae Choe, Junkyoung Kim, Ji-Eun Lee, Bong-Woo Lee, Jeong Hee Nam, Moon Park, Youn-Il Jo, Sung-Hwan Database (Oxford) Database Tool It is necessary for molecular breeders to overcome the difficulties in applying abundant genomic information to crop breeding. Candidate orthologs would be discovered more efficiently in less-studied crops if the information gained from studies of related crops were used. We developed a comparative analysis tool and web-based genome viewer to identify orthologous genes based synteny as well as sequence similarity between tomato, pepper and potato. The tool has a step-by-step interface with multiple viewing levels to support the easy and accurate exploration of functional orthologs. Furthermore, it provides access to single nucleotide-polymorphism markers from the massive genetic resource pool in order to accelerate the development of molecular markers for candidate orthologs in the Solanaceae. This tool provides a bridge between genome data and breeding by supporting effective marker development, data utilization and communication. Database URL: http://tgsol.seeders.co.kr/scomp/ Oxford University Press 2018-06-03 /pmc/articles/PMC6007222/ /pubmed/29873704 http://dx.doi.org/10.1093/database/bay047 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Tool
Choe, Junkyoung
Kim, Ji-Eun
Lee, Bong-Woo
Lee, Jeong Hee
Nam, Moon
Park, Youn-Il
Jo, Sung-Hwan
A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
title A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
title_full A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
title_fullStr A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
title_full_unstemmed A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
title_short A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae
title_sort comparative synteny analysis tool for target-gene snp marker discovery: connecting genomics data to breeding in solanaceae
topic Database Tool
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007222/
https://www.ncbi.nlm.nih.gov/pubmed/29873704
http://dx.doi.org/10.1093/database/bay047
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