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Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study

BACKGROUND: Gains in life expectancy through optimal control of HIV infection with antiretroviral therapy (ART) may be threatened if other comorbidities, such as diabetes, are not optimally managed. METHODS: We analyzed cross-sectional data of the Women’s Interagency HIV Study (WIHS) from 2001, 2006...

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Autores principales: Colasanti, Jonathan, Galaviz, Karla I, Christina Mehta, C, Palar, Kartika, Schneider, Michael F, Tien, Phyllis, Adimora, Adaora A, Alcaide, Maria, Cohen, Mardge H, Gustafson, Deborah, Karim, Roksana, Merenstein, Daniel, Sharma, Anjali, Wingood, Gina, Marconi, Vincent C, Ofotokun, Ighovwerha, Ali, Mohammed K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007350/
https://www.ncbi.nlm.nih.gov/pubmed/29942823
http://dx.doi.org/10.1093/ofid/ofy121
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author Colasanti, Jonathan
Galaviz, Karla I
Christina Mehta, C
Palar, Kartika
Schneider, Michael F
Tien, Phyllis
Adimora, Adaora A
Alcaide, Maria
Cohen, Mardge H
Gustafson, Deborah
Karim, Roksana
Merenstein, Daniel
Sharma, Anjali
Wingood, Gina
Marconi, Vincent C
Ofotokun, Ighovwerha
Ali, Mohammed K
author_facet Colasanti, Jonathan
Galaviz, Karla I
Christina Mehta, C
Palar, Kartika
Schneider, Michael F
Tien, Phyllis
Adimora, Adaora A
Alcaide, Maria
Cohen, Mardge H
Gustafson, Deborah
Karim, Roksana
Merenstein, Daniel
Sharma, Anjali
Wingood, Gina
Marconi, Vincent C
Ofotokun, Ighovwerha
Ali, Mohammed K
author_sort Colasanti, Jonathan
collection PubMed
description BACKGROUND: Gains in life expectancy through optimal control of HIV infection with antiretroviral therapy (ART) may be threatened if other comorbidities, such as diabetes, are not optimally managed. METHODS: We analyzed cross-sectional data of the Women’s Interagency HIV Study (WIHS) from 2001, 2006, and 2015. We estimated the proportions of HIV-positive and HIV-negative women with diabetes who were engaged in care and achieved treatment goals (hemoglobin A1c [A1c] <7.0%, blood pressure [BP] <140/90 mmHg, low-density lipoprotein [LDL] cholesterol <100 mg/dL, not smoking) and viral suppression. Repeated-measures models were used to estimate the adjusted prevalence of achieving each diabetes treatment goal at each time point, by HIV status. RESULTS: We included 486 HIV-positive and 258 HIV-negative women with diabetes. In 2001, 91.8% visited a health care provider, 60.7% achieved the A1c target, 70.5% achieved the BP target, 38.5% achieved the LDL cholesterol target, 49.2% were nonsmokers, 23.3% achieved combined ABC targets (A1c, BP, and cholesterol), and 10.9% met combined ABC targets and did not smoke. There were no differences by HIV status, and patterns were similar in 2006 and 2015. Among HIV-positive women, viral suppression increased from 41% in 2001 to 87% in 2015 compared with 8% and 13% achieving the ABC goals and not smoking. Viral suppression was not associated with achievement of diabetes care goals. CONCLUSIONS: Successful management of HIV is outpacing that of diabetes. Future studies are needed to identify factors associated with gaps in the HIV–diabetes care continuum and design interventions to better integrate effective diabetes management into HIV care.
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spelling pubmed-60073502018-06-25 Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study Colasanti, Jonathan Galaviz, Karla I Christina Mehta, C Palar, Kartika Schneider, Michael F Tien, Phyllis Adimora, Adaora A Alcaide, Maria Cohen, Mardge H Gustafson, Deborah Karim, Roksana Merenstein, Daniel Sharma, Anjali Wingood, Gina Marconi, Vincent C Ofotokun, Ighovwerha Ali, Mohammed K Open Forum Infect Dis Major Article BACKGROUND: Gains in life expectancy through optimal control of HIV infection with antiretroviral therapy (ART) may be threatened if other comorbidities, such as diabetes, are not optimally managed. METHODS: We analyzed cross-sectional data of the Women’s Interagency HIV Study (WIHS) from 2001, 2006, and 2015. We estimated the proportions of HIV-positive and HIV-negative women with diabetes who were engaged in care and achieved treatment goals (hemoglobin A1c [A1c] <7.0%, blood pressure [BP] <140/90 mmHg, low-density lipoprotein [LDL] cholesterol <100 mg/dL, not smoking) and viral suppression. Repeated-measures models were used to estimate the adjusted prevalence of achieving each diabetes treatment goal at each time point, by HIV status. RESULTS: We included 486 HIV-positive and 258 HIV-negative women with diabetes. In 2001, 91.8% visited a health care provider, 60.7% achieved the A1c target, 70.5% achieved the BP target, 38.5% achieved the LDL cholesterol target, 49.2% were nonsmokers, 23.3% achieved combined ABC targets (A1c, BP, and cholesterol), and 10.9% met combined ABC targets and did not smoke. There were no differences by HIV status, and patterns were similar in 2006 and 2015. Among HIV-positive women, viral suppression increased from 41% in 2001 to 87% in 2015 compared with 8% and 13% achieving the ABC goals and not smoking. Viral suppression was not associated with achievement of diabetes care goals. CONCLUSIONS: Successful management of HIV is outpacing that of diabetes. Future studies are needed to identify factors associated with gaps in the HIV–diabetes care continuum and design interventions to better integrate effective diabetes management into HIV care. Oxford University Press 2018-05-22 /pmc/articles/PMC6007350/ /pubmed/29942823 http://dx.doi.org/10.1093/ofid/ofy121 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Article
Colasanti, Jonathan
Galaviz, Karla I
Christina Mehta, C
Palar, Kartika
Schneider, Michael F
Tien, Phyllis
Adimora, Adaora A
Alcaide, Maria
Cohen, Mardge H
Gustafson, Deborah
Karim, Roksana
Merenstein, Daniel
Sharma, Anjali
Wingood, Gina
Marconi, Vincent C
Ofotokun, Ighovwerha
Ali, Mohammed K
Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
title Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
title_full Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
title_fullStr Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
title_full_unstemmed Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
title_short Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
title_sort room for improvement: the hiv–diabetes care continuum over 15 years in the women’s interagency hiv study
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007350/
https://www.ncbi.nlm.nih.gov/pubmed/29942823
http://dx.doi.org/10.1093/ofid/ofy121
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