The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA

During infection, bacteriophage T4 produces the MotA transcription factor that redirects the host RNA polymerase to the expression of T4 middle genes. The C-terminal ‘double-wing’ domain of MotA binds specifically to the MotA box motif of middle T4 promoters. We report the crystal structure of this...

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Detalles Bibliográficos
Autores principales: Cuypers, Maxime G, Robertson, Rosanna M, Knipling, Leslie, Waddell, M Brett, Moon, Kyung, Hinton, Deborah M, White, Stephen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007404/
https://www.ncbi.nlm.nih.gov/pubmed/29718457
http://dx.doi.org/10.1093/nar/gky292

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