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LRP/LR specific antibody IgG1-iS18 impedes neurodegeneration in Alzheimer's disease mice

Alzheimer’s disease (AD) is a neurodegenerative disease caused by accumulation of amyloid beta (Aβ) plaque and neurofibrillary tangle formation. We have shown in vitro, that knock-down and blockade of the 37 kDa/67 kDa Laminin Receptor (LRP/LR) resulted in reduced Aβ induced cytotoxicity and Aβ accu...

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Detalles Bibliográficos
Autores principales:	Ferreira, Eloise, Bignoux, Monique J., Otgaar, Tyrone C., Tagliatti, Nicolas, Jovanovic, Katarina, Letsolo, Boitelo T., Weiss, Stefan F.T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007457/ https://www.ncbi.nlm.nih.gov/pubmed/29930750 http://dx.doi.org/10.18632/oncotarget.25473

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