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Global metabolite profiling analysis of lipotoxicity in HER2/neu-positive breast cancer cells
Recent work has shown that HER2/neu-positive breast cancer cells rely on a unique Warburg-like metabolism for survival and aggressive behavior. These cells are dependent on fatty acid (FA) synthesis, show markedly increased levels of stored fats and disruption of the synthetic process results in apo...
Autores principales: | Baumann, Jan, Kokabee, Mostafa, Wong, Jason, Balasubramaniyam, Rakshika, Sun, Yan, Conklin, Douglas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007458/ https://www.ncbi.nlm.nih.gov/pubmed/29930756 http://dx.doi.org/10.18632/oncotarget.25500 |
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