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Global metabolite profiling analysis of lipotoxicity in HER2/neu-positive breast cancer cells

Recent work has shown that HER2/neu-positive breast cancer cells rely on a unique Warburg-like metabolism for survival and aggressive behavior. These cells are dependent on fatty acid (FA) synthesis, show markedly increased levels of stored fats and disruption of the synthetic process results in apo...

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Detalles Bibliográficos
Autores principales: Baumann, Jan, Kokabee, Mostafa, Wong, Jason, Balasubramaniyam, Rakshika, Sun, Yan, Conklin, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007458/
https://www.ncbi.nlm.nih.gov/pubmed/29930756
http://dx.doi.org/10.18632/oncotarget.25500

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