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Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance

BACKGROUND: Ovarian cancer is associated with poor prognostic outcome due to late diagnosis and to intrinsic and acquired resistance to platinum-based chemotherapy in a large number of patients. This chemoresistance is acquired through the peritoneal and ascites microenvironment by several released...

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Detalles Bibliográficos
Autores principales: Le Naour, Augustin, Mevel, Renaud, Thibault, Benoit, Courtais, Elise, Chantalat, Elodie, Delord, Jean Pierre, Couderc, Bettina, Guillermet-Guibert, Julie, Martinez, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007481/
https://www.ncbi.nlm.nih.gov/pubmed/29930760
http://dx.doi.org/10.18632/oncotarget.25513

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