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Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance
BACKGROUND: Ovarian cancer is associated with poor prognostic outcome due to late diagnosis and to intrinsic and acquired resistance to platinum-based chemotherapy in a large number of patients. This chemoresistance is acquired through the peritoneal and ascites microenvironment by several released...
Autores principales: | Le Naour, Augustin, Mevel, Renaud, Thibault, Benoit, Courtais, Elise, Chantalat, Elodie, Delord, Jean Pierre, Couderc, Bettina, Guillermet-Guibert, Julie, Martinez, Alejandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007481/ https://www.ncbi.nlm.nih.gov/pubmed/29930760 http://dx.doi.org/10.18632/oncotarget.25513 |
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