Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress

The MUS81 complex is crucial for preserving genome stability through the resolution of branched DNA intermediates in mitosis. However, untimely activation of the MUS81 complex in S-phase is dangerous. Little is known about the regulation of the human MUS81 complex and how deregulated activation affe...

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Detalles Bibliográficos
Autores principales: Palma, Anita, Pugliese, Giusj Monia, Murfuni, Ivana, Marabitti, Veronica, Malacaria, Eva, Rinalducci, Sara, Minoprio, Anna, Sanchez, Massimo, Mazzei, Filomena, Zolla, Lello, Franchitto, Annapaola, Pichierri, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007509/
https://www.ncbi.nlm.nih.gov/pubmed/29850896
http://dx.doi.org/10.1093/nar/gky280

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