Cargando…

Dynamic Cellular Integration Drives Functional Assembly of the Heart’s Pacemaker Complex

Impulses generated by a multicellular, bioelectric signaling center termed the sinoatrial node (SAN) stimulate the rhythmic contraction of the heart. The SAN consists of a network of electrochemically oscillating pacemaker cells encased in a heterogeneous connective tissue microenvironment. Although...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bressan, Michael, Henley, Trevor, Louie, Jonathan D., Liu, Gary, Christodoulou, Danos, Bai, Xue, Taylor, Joan, Seidman, Christine E., Seidman, J.G., Mikawa, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007983/ https://www.ncbi.nlm.nih.gov/pubmed/29791840 http://dx.doi.org/10.1016/j.celrep.2018.04.075

Ejemplares similares

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis
por: Delgado-Olguín, Paul, et al.
Publicado: (2012)

Hypertrophic cardiomyopathy: Translating cellular cross talk into therapeutics
por: Teekakirikul, Polakit, et al.
Publicado: (2012)

Simplified platform for mosaic in vivo analysis of cellular maturation in the developing heart
por: Goudy, Julie, et al.
Publicado: (2019)

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro
por: DeLaughter, Daniel M., et al.
Publicado: (2016)

Local tissue mechanics control cardiac pacemaker cell embryonic patterning
por: Henley, Trevor, et al.
Publicado: (2023)

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function
por: Sun, Xin, et al.
Publicado: (2017)

Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction
por: Bressan, Michael C., et al.
Publicado: (2014)

Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases
por: Rios, Xavier, et al.
Publicado: (2012)

Optical Electrophysiology in the Developing Heart
por: Thomas, Kandace, et al.
Publicado: (2018)

Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis
por: Easterling, Marietta, et al.
Publicado: (2021)

Dissecting spatio-temporal protein networks driving human heart development and related disorders
por: Lage, Kasper, et al.
Publicado: (2010)

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity
por: Zhang, Bing, et al.
Publicado: (2013)

Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans
por: Zhang, Hao, et al.
Publicado: (2022)

Microinjection-based System for In Vivo Implantation of Embryonic Cardiomyocytes in the Avian Embryo
por: Henley, Trevor, et al.
Publicado: (2019)

Driving restrictions in patients with implantable cardioverter defibrillators and pacemakers
por: Watanabe, Eiichi, et al.
Publicado: (2017)

A Simulation Study on the Pacing and Driving of the Biological Pacemaker
por: Zhang, Yue, et al.
Publicado: (2020)

An application of pacemaker respiratory monitoring system for the prediction of heart failure
por: Koyama, Takashi, et al.
Publicado: (2019)

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart
por: Alcalai, Ronny, et al.
Publicado: (2021)

Right heart perforation by pacemaker leads
por: Banaszewski, Marek, et al.
Publicado: (2012)

Contested knowledge : social theory today /
por: Seidman, Steven
Publicado: (2008)

The Ultimate Guide to Sales Training: Potent Tactics to Accelerate Sales Performance
por: Seidman, Dan
Publicado: (2012)

How: why how we do anything means everything-- in business (and in life)
por: Seidman, Dov
Publicado: (2007)

How: why how we do anything means everything
por: Seidman, Dov
Publicado: (2007)

The Secret Language of Influence: Master the One Skill Every Sales Pro Needs
por: Seidman, Dan
Publicado: (2012)

The Star Factor
por: Seidman, William
Publicado: (2013)

Does SDG 3 have an adequate theory of change for improving health systems performance?
por: Seidman, Gabriel
Publicado: (2017)

That’s All She Wrote
por: Seidman, Charlotte S.
Publicado: (2022)

A Love Rooted Deep in the Appalachian Mountains: One Part of the Legacy of Doug Scutchfield
por: Seidman, Charlotte S.
Publicado: (2022)

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes
por: Alamo, Lorenzo, et al.
Publicado: (2017)

Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish
por: Kidokoro, Hinako, et al.
Publicado: (2022)

On The Mechanism of Spontaneous Impulse Generation in the Pacemaker of the Heart
por: Trautwein, Wolfgang, et al.
Publicado: (1961)

An overlooked case of pacemaker-related heart failure
por: Patel, Hitesh C, et al.
Publicado: (2017)

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection
por: Herman, Daniel S, et al.
Publicado: (2009)

PC16. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia
por: Timberlake, Andrew T., et al.
Publicado: (2023)

1. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia
por: Timberlake, Andrew T., et al.
Publicado: (2023)

Interviewing as qualitative research : a guide for researchers in education and the social sciences /
por: Seidman, Irving, 1937-
Publicado: (1998)

Building global partnerships for library cooperation
por: Seidman, Ruth K
Publicado: (1992)

Interviewing as qualitative research : a guide for researchers in education and the social sciences
por: Seidman, Irving, 1937-
Publicado: (2013)

T(mem) time: Memory T-Cells in Cardiac Allograft Vasculopathy: Editorial to: “Memory T Cells Mediate Cardiac Allograft Vasculopathy and are Inactivated by Anti-OX40L Monoclonal Antibody” by Hao Wang et al.
por: Seidman, Michael A.
Publicado: (2014)

Glutamate drives ‘local Ca(2+) release’ in cardiac pacemaker cells
por: Xie, Duanyang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t0d3r38l0grh572bu3vnqsh96h