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Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
Aortic stiffening is a major independent risk factor for cardiovascular diseases, cognitive dysfunction, and other chronic disorders of aging. Mitochondria-derived reactive oxygen species are a key source of arterial oxidative stress, which may contribute to arterial stiffening by promoting adverse...
Autores principales: | Gioscia-Ryan, Rachel A., Battson, Micah L., Cuevas, Lauren M., Eng, Jason S., Murphy, Michael P., Seals, Douglas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008077/ https://www.ncbi.nlm.nih.gov/pubmed/29074712 http://dx.doi.org/10.1152/japplphysiol.00670.2017 |
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