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Escape from homeostasis: spinal microcircuits and progression of amyotrophic lateral sclerosis
In amyotrophic lateral sclerosis (ALS), loss of motoneuron function leads to weakness and, ultimately, respiratory failure and death. Regardless of the initial pathogenic factors, motoneuron loss follows a specific pattern: the largest α-motoneurons die before smaller α-motoneurons, and γ-motoneuron...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Physiological Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008087/ https://www.ncbi.nlm.nih.gov/pubmed/29384454 http://dx.doi.org/10.1152/jn.00331.2017 |