Neonatal Colonic Inflammation Epigenetically Aggravates Epithelial Inflammatory Responses to Injury in Adult Life

BACKGROUND & AIMS: Early life adversity is considered a risk factor for the development of gastrointestinal diseases, including inflammatory bowel disease. We hypothesized that early life colonic inflammation causes susceptibility to aggravated overexpression of interleukin (IL)1β. METHODS: We d...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaoying S., Winston, John H., Luo, Xiuju, Kline, Kevin T., Nayeem, Syed Z., Cong, Yingzi, Savidge, Tor C., Dashwood, Roderick H., Powell, Don W., Li, Qingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008258/
https://www.ncbi.nlm.nih.gov/pubmed/29928672
http://dx.doi.org/10.1016/j.jcmgh.2018.02.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008258/
https://www.ncbi.nlm.nih.gov/pubmed/29928672
http://dx.doi.org/10.1016/j.jcmgh.2018.02.014

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