Cargando…

Neonatal Colonic Inflammation Epigenetically Aggravates Epithelial Inflammatory Responses to Injury in Adult Life

BACKGROUND & AIMS: Early life adversity is considered a risk factor for the development of gastrointestinal diseases, including inflammatory bowel disease. We hypothesized that early life colonic inflammation causes susceptibility to aggravated overexpression of interleukin (IL)1β. METHODS: We d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Xiaoying S., Winston, John H., Luo, Xiuju, Kline, Kevin T., Nayeem, Syed Z., Cong, Yingzi, Savidge, Tor C., Dashwood, Roderick H., Powell, Don W., Li, Qingjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008258/ https://www.ncbi.nlm.nih.gov/pubmed/29928672 http://dx.doi.org/10.1016/j.jcmgh.2018.02.014

Ejemplares similares

Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7
por: Xiao, Ying, et al.
Publicado: (2022)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

Epigenetic Regulation of Enteric Neurotransmission by Gut Bacteria
por: Savidge, Tor C.
Publicado: (2016)

Targeting Epigenetic ‘Readers’ with Natural Compounds for Cancer Interception
por: Damiani, Elisabetta, et al.
Publicado: (2020)

Neonatal Antibiotics Disrupt Motility and Enteric Neural Circuits in Mouse Colon
por: Hung, Lin Y., et al.
Publicado: (2019)

Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats
por: Orner, Gayle A, et al.
Publicado: (2006)

A role for low-abundance miRNAs in colon cancer: the miR-206/Krüppel-like factor 4 (KLF4) axis
por: Parasramka, Mansi A, et al.
Publicado: (2012)

Cancer interception by interceptor molecules: mechanistic, preclinical and human translational studies with chlorophylls
por: Dashwood, Roderick H.
Publicado: (2021)

Microbiota dysbiosis and its pathophysiological significance in bowel obstruction
por: Hegde, Shrilakshmi, et al.
Publicado: (2018)

Neonatal Colonic Inflammation: An Epigenetic Trigger of Adult Disease
por: Strober, Warren
Publicado: (2018)

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly
por: Rajendran, Praveen, et al.
Publicado: (2011)

Deacetylase Plus Bromodomain Inhibition Downregulates ERCC2 and Suppresses the Growth of Metastatic Colon Cancer Cells
por: Kapoor, Sabeeta, et al.
Publicado: (2021)

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates
por: Rajendran, Praveen, et al.
Publicado: (2013)

Predicting Inflammatory Bowel Disease Symptoms Onset: Nitrous Take on Gut Bacteria Is No Laughing Matter
por: Savidge, Tor
Publicado: (2020)

BRD9 Inhibition by Natural Polyphenols Targets DNA Damage/Repair and Apoptosis in Human Colon Cancer Cells
por: Kapoor, Sabeeta, et al.
Publicado: (2022)

Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heart
por: Tang, Yanbo, et al.
Publicado: (2021)

S-Nitrosothiol Signals in the Enteric Nervous System: Lessons Learnt from Big Brother
por: Savidge, Tor C.
Publicado: (2011)

Glial Orchestrated Neurodegeneration: An Important Crossroad for Neural Stem Cell Therapy to the Intestine
por: Savidge, Tor C.
Publicado: (2015)

CCAR1 and CCAR2 as gene chameleons with antagonistic duality: Preclinical, human translational, and mechanistic basis
por: Johnson, Gavin S., et al.
Publicado: (2020)

Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon
por: Rajendran, Praveen, et al.
Publicado: (2015)

The Enterotoxicity of Clostridium difficile Toxins
por: Sun, Xingmin, et al.
Publicado: (2010)

Sex-Bias in Irritable Bowel Syndrome: Linking Steroids to the Gut-Brain Axis
por: So, Sik Yu, et al.
Publicado: (2021)

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells
por: Rajendran, Praveen, et al.
Publicado: (2011)

The food additive EDTA aggravates colitis and colon carcinogenesis in mouse models
por: Evstatiev, Rayko, et al.
Publicado: (2021)

Gut Microbiota Dysbiosis Aggravates Mycoplasma gallisepticum Colonization in the Chicken Lung
por: Wang, Jian, et al.
Publicado: (2021)

Occurrence of bla(NDM) Variants Among Enterobacteriaceae From a Neonatal Intensive Care Unit in a Northern India Hospital
por: Ahmad, Nayeem, et al.
Publicado: (2018)

The colonic interleukin-19 aggravates the dextran sodium sulfate/stress-induced comorbidities due to colitis and anxiety
por: Li, Qiongyu, et al.
Publicado: (2023)

Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice
por: Tsuji, Shunichiro, et al.
Publicado: (2020)

HDAC8 and STAT3 repress BMF gene activity in colon cancer cells
por: Kang, Y, et al.
Publicado: (2014)

Sudden aggravated CD8(+) mycosis fungoides accompanied by hidden adenocarcinoma of the colon
por: Ahn, Hye-Jin, et al.
Publicado: (2017)

Synergistic apoptosis following endoplasmic reticulum stress aggravation in mucinous colon cancer
por: Dilly, Ashok K., et al.
Publicado: (2020)

Metabolism and Cancer: Old and New Players
por: Cerella, Claudia, et al.
Publicado: (2013)

Pancreastatin Reduces Alternatively Activated Macrophages, Disrupts the Epithelial Homeostasis and Aggravates Colonic Inflammation. A Descriptive Analysis
por: Eissa, Nour, et al.
Publicado: (2021)

Neonatal antibiotics have long term sex‐dependent effects on the enteric nervous system
por: Poon, Sabrina S. B., et al.
Publicado: (2022)

Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation
por: Kvakova, Monika, et al.
Publicado: (2021)

Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice
por: Li, Tao, et al.
Publicado: (2020)

Dietary spinach reshapes the gut microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics
por: Chen, Ying-Shiuan, et al.
Publicado: (2021)

CD4(+) T cells aggravate hemorrhagic brain injury
por: Shi, Samuel X., et al.
Publicado: (2023)

1775. Microbiome-Based Classifiers Accurately Differentiate Infectious Diarrhea From Functional Gastrointestinal Disorders and Provide Population-Scale Confidence Measures of Fecal Microbiota Restoration in Recurrent C. DifficileInfection
por: Wu, Qinglong, et al.
Publicado: (2018)

Inhibitory Activity of Green and Black Tea in a Free Radical‐generating System Using 2‐Amino‐3‐methylimidazo[4,5‐f]quinoline as Substrate
por: Hasaniya, Nahidh, et al.
Publicado: (1997)

Cannot write session to /tmp/vufind_sessions/sess_n7fr33tt4ji99oed2omvpgmt6i