Uniform intratumoral distribution of radioactivity produced using two different radioagents, (64)Cu-cyclam-RAFT-c(-RGDfK-)(4) and (64)Cu-ATSM, improves therapeutic efficacy in a small animal tumor model

BACKGROUND: The present study proposed a new concept for targeted radionuclide therapy (TRT) to improve the intratumoral distribution of radioactivity using two different radiopharmaceuticals. We examined the efficacy of a combination of a tetrameric cyclic Arg-Gly-Asp (cRGD) peptide-based radiophar...

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Detalles Bibliográficos
Autores principales: Jin, Zhao-Hui, Tsuji, Atsushi B., Degardin, Mélissa, Sugyo, Aya, Yoshii, Yukie, Nagatsu, Kotaro, Zhang, Ming-Rong, Fujibayashi, Yasuhisa, Dumy, Pascal, Boturyn, Didier, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008272/
https://www.ncbi.nlm.nih.gov/pubmed/29923139
http://dx.doi.org/10.1186/s13550-018-0407-3

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