Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway

Mitochondria supply ~90% of the ATP required for contractile function in cardiac cells. While adult cardiomyocytes preferentially utilize fatty acids as a fuel source for oxidative phosphorylation, cardiac mitochondria can switch to other substrates when required. This change is driven in part by a...

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Detalles Bibliográficos
Autores principales: Thapa, Dharendra, Stoner, Michael W., Zhang, Manling, Xie, Bingxian, Manning, Janet R., Guimaraes, Danielle, Shiva, Sruti, Jurczak, Michael J., Scott, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008287/
https://www.ncbi.nlm.nih.gov/pubmed/29909017
http://dx.doi.org/10.1016/j.redox.2018.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008287/
https://www.ncbi.nlm.nih.gov/pubmed/29909017
http://dx.doi.org/10.1016/j.redox.2018.06.003

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