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Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing
Three of the eight RNA segments encoded by the influenza A virus (IAV) undergo alternative splicing to generate distinct proteins. Previously, we found that host proteins hnRNP K and NS1-BP regulate IAV M segment splicing, but the mechanistic details were unknown. Here we show NS1-BP and hnRNP K bin...
Autores principales: | Thompson, Matthew G., Muñoz-Moreno, Raquel, Bhat, Prasanna, Roytenberg, Renat, Lindberg, John, Gazzara, Matthew R., Mallory, Michael J., Zhang, Ke, García-Sastre, Adolfo, Fontoura, Beatriz M. A., Lynch, Kristen W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008300/ https://www.ncbi.nlm.nih.gov/pubmed/29921878 http://dx.doi.org/10.1038/s41467-018-04779-4 |
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