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Imaging in Biologically-Relevant Environments with AFM Using Stiff qPlus Sensors
High-resolution imaging of soft biological samples with atomic force microscopy (AFM) is challenging because they must be imaged with small forces to prevent deformation. Typically, AFM of those samples is performed with soft silicon cantilevers (k ≈ 0.1–10 N/m) and optical detection in a liquid env...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008343/ https://www.ncbi.nlm.nih.gov/pubmed/29921947 http://dx.doi.org/10.1038/s41598-018-27608-6 |