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Detection of genetic cardiac diseases by Ca(2+) transient profiles using machine learning methods

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have revolutionized cardiovascular research. Abnormalities in Ca(2+) transients have been evident in many cardiac disease models. We have shown earlier that, by exploiting computational machine learning methods, normal Ca(2+) tra...

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Detalles Bibliográficos
Autores principales: Juhola, Martti, Joutsijoki, Henry, Penttinen, Kirsi, Aalto-Setälä, Katriina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008430/
https://www.ncbi.nlm.nih.gov/pubmed/29921843
http://dx.doi.org/10.1038/s41598-018-27695-5

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