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Detection of genetic cardiac diseases by Ca(2+) transient profiles using machine learning methods
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have revolutionized cardiovascular research. Abnormalities in Ca(2+) transients have been evident in many cardiac disease models. We have shown earlier that, by exploiting computational machine learning methods, normal Ca(2+) tra...
Autores principales: | Juhola, Martti, Joutsijoki, Henry, Penttinen, Kirsi, Aalto-Setälä, Katriina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008430/ https://www.ncbi.nlm.nih.gov/pubmed/29921843 http://dx.doi.org/10.1038/s41598-018-27695-5 |
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