Patient derived organoids to model rare prostate cancer phenotypes

A major hurdle in the study of rare tumors is a lack of existing preclinical models. Neuroendocrine prostate cancer is an uncommon and aggressive histologic variant of prostate cancer that may arise de novo or as a mechanism of treatment resistance in patients with pre-existing castration-resistant...

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Detalles Bibliográficos
Autores principales: Puca, Loredana, Bareja, Rohan, Prandi, Davide, Shaw, Reid, Benelli, Matteo, Karthaus, Wouter R., Hess, Judy, Sigouros, Michael, Donoghue, Adam, Kossai, Myriam, Gao, Dong, Cyrta, Joanna, Sailer, Verena, Vosoughi, Aram, Pauli, Chantal, Churakova, Yelena, Cheung, Cynthia, Deonarine, Lesa Dayal, McNary, Terra J., Rosati, Rachele, Tagawa, Scott T., Nanus, David M., Mosquera, Juan Miguel, Sawyers, Charles L., Chen, Yu, Inghirami, Giorgio, Rao, Rema A., Grandori, Carla, Elemento, Olivier, Sboner, Andrea, Demichelis, Francesca, Rubin, Mark A., Beltran, Himisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008438/
https://www.ncbi.nlm.nih.gov/pubmed/29921838
http://dx.doi.org/10.1038/s41467-018-04495-z

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