Cargando…

Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease

Iron is suggested to play a detrimental role in the progression of chronic kidney disease (CKD). The kidney recycles iron back into the circulation. However, the localization of proteins relevant for physiological tubular iron handling and their potential role in CKD remain unclear. We examined asso...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Raaij, Sanne, van Swelm, Rachel, Bouman, Karlijn, Cliteur, Maaike, van den Heuvel, Marius C., Pertijs, Jeanne, Patel, Dominic, Bass, Paul, van Goor, Harry, Unwin, Robert, Srai, Surjit Kaila, Swinkels, Dorine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008459/ https://www.ncbi.nlm.nih.gov/pubmed/29921869 http://dx.doi.org/10.1038/s41598-018-27107-8

Ejemplares similares

Publisher Correction: Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
por: van Raaij, Sanne, et al.
Publicado: (2018)

Iron uptake by ZIP8 and ZIP14 in human proximal tubular epithelial cells
por: van Raaij, S. E. G., et al.
Publicado: (2019)

Kidney tubule iron loading in experimental focal segmental glomerulosclerosis
por: van Swelm, Rachel P. L., et al.
Publicado: (2022)

Quercetin inhibits intestinal non-haem iron absorption by regulating iron metabolism genes in the tissues
por: Lesjak, Marija, et al.
Publicado: (2018)

Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone
por: Diepeveen, Laura, et al.
Publicado: (2021)

Role of Dietary Flavonoids in Iron Homeostasis
por: Lesjak, Marija, et al.
Publicado: (2019)

Urinary Hepcidin Levels in Iron-Deficient and Iron-Supplemented Piglets Correlate with Hepcidin Hepatic mRNA and Serum Levels and with Body Iron Status
por: Staroń, Robert, et al.
Publicado: (2015)

The role of iron in the skin and cutaneous wound healing
por: Wright, Josephine A., et al.
Publicado: (2014)

Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption
por: Staroń, Robert, et al.
Publicado: (2017)

Phytoestrogens modulate hepcidin expression by Nrf2: Implications for dietary control of iron absorption
por: Bayele, Henry K., et al.
Publicado: (2015)

A disease-causing mutation K240E disrupts ferroportin trafficking by SUMO (ferroportin SUMOylation)
por: Bayele, Henry K., et al.
Publicado: (2021)

Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury
por: Diepeveen, Laura E., et al.
Publicado: (2022)

Iron refractory iron deficiency anemia: a heterogeneous disease that is not always iron refractory
por: Donker, Albertine E., et al.
Publicado: (2016)

Comparative Evaluation of Sucrosomial Iron and Iron Oxide Nanoparticles as Oral Supplements in Iron Deficiency Anemia in Piglets
por: Mazgaj, Rafał, et al.
Publicado: (2021)

Quercetin Inhibits Intestinal Iron Absorption and Ferroportin Transporter Expression In Vivo and In Vitro
por: Lesjak, Marija, et al.
Publicado: (2014)

Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis
por: van Swelm, Rachel P. L., et al.
Publicado: (2018)

Handling iron in restorative neuroscience
por: Routhe, Lisa Junl, et al.
Publicado: (2015)

First-in-human Phase I studies of PRS-080#22, a hepcidin antagonist, in healthy volunteers and patients with chronic kidney disease undergoing hemodialysis
por: Renders, Lutz, et al.
Publicado: (2019)

Iron Supplementation in Suckling Piglets: How to Correct Iron Deficiency Anemia without Affecting Plasma Hepcidin Levels
por: Starzyński, Rafał R., et al.
Publicado: (2013)

Pharmacokinetics of Ferric Pyrophosphate Citrate, a Novel Iron Salt, Administered Intravenously to Healthy Volunteers
por: Pratt, Raymond D., et al.
Publicado: (2016)

Transferrin Saturation/Hepcidin Ratio Discriminates TMPRSS6-Related Iron Refractory Iron Deficiency Anemia from Patients with Multi-Causal Iron Deficiency Anemia
por: van der Staaij, Hilde, et al.
Publicado: (2022)

Iron deficiency, with and without anaemia, across strata of kidney function in kidney transplant recipients
por: Ayerdem, Gizem, et al.
Publicado: (2021)

Iron Availability Increases the Pathogenic Potential of Salmonella Typhimurium and Other Enteric Pathogens at the Intestinal Epithelial Interface
por: Kortman, Guus A. M., et al.
Publicado: (2012)

The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload
por: Mohammad, Goran, et al.
Publicado: (2021)

Iron therapy mitigates chronic kidney disease progression by regulating intracellular iron status of kidney macrophages
por: Patino, Edwin, et al.
Publicado: (2023)

Iron deficiency impairs contractility of human cardiomyocytes through decreased mitochondrial function
por: Hoes, Martijn F., et al.
Publicado: (2018)

“Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels
por: Nairz, Manfred, et al.
Publicado: (2017)

Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets
por: Mazgaj, Rafał, et al.
Publicado: (2020)

Iron deficiency after kidney transplantation
por: Vinke, Joanna Sophia J, et al.
Publicado: (2020)

Impact of iron status on kidney outcomes in kidney transplant recipients
por: Kim, Hyo Jeong, et al.
Publicado: (2023)

Iron Status and the Acute Post-Exercise Hepcidin Response in Athletes
por: Peeling, Peter, et al.
Publicado: (2014)

Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention
por: Weiss, Avital, et al.
Publicado: (2018)

A possible role for hepcidin in the detection of iron deficiency in severely anaemic HIV-infected patients in Malawi
por: Huibers, Minke H. W., et al.
Publicado: (2020)

Disrupted iron regulation in the brain and periphery in cocaine addiction
por: Ersche, K D, et al.
Publicado: (2017)

Association of different iron deficiency cutoffs with adverse outcomes in chronic kidney disease
por: Eisenga, Michele F., et al.
Publicado: (2018)

Iron Status of Cats with Chronic Kidney Disease
por: Gest, J., et al.
Publicado: (2015)

Measurement of iron status in chronic kidney disease
por: Hayes, Wesley
Publicado: (2018)

Iron Is Filtered by the Kidney and Is Reabsorbed by the Proximal Tubule
por: Wareing, Mark, et al.
Publicado: (2021)

Biomarkers of iron metabolism in chronic kidney disease
por: Tomasz, Glogowski, et al.
Publicado: (2020)

Iron overload and impaired iron handling contribute to the dystrophic pathology in models of Duchenne muscular dystrophy
por: Alves, Francesca M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f90cs4o1qfou23l1ile00ql789