Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

BACKGROUND: Substantial evidence supports an association between use of menopausal hormone therapy and decreased colorectal cancer (CRC) risk, indicating a role of exogenous sex hormones in CRC development. However, findings on endogenous oestrogen exposure and CRC are inconsistent. METHODS: We used...

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Detalles Bibliográficos
Autores principales: Neumeyer, Sonja, Banbury, Barbara L., Arndt, Volker, Berndt, Sonja I., Bezieau, Stephane, Bien, Stephanie A., Buchanan, Dan D., Butterbach, Katja, Caan, Bette J., Campbell, Peter T., Casey, Graham, Chan, Andrew T., Chanock, Stephen J., Dai, James Y., Gallinger, Steven, Giovannucci, Edward L., Giles, Graham G., Grady, William M., Hampe, Jochen, Hoffmeister, Michael, Hopper, John L., Hsu, Li, Jenkins, Mark A., Joshi, Amit, Larsson, Susanna C., Le Marchand, Loic, Lindblom, Annika, Moreno, Victor, Lemire, Mathieu, Li, Li, Lin, Yi, Offit, Kenneth, Newcomb, Polly A., Pharaoh, Paul D., Potter, John D., Qi, Lihong, Rennert, Gad, Schafmayer, Clemens, Schoen, Robert E., Slattery, Martha L., Song, Mingyang, Ulrich, Cornelia M., Win, Aung K., White, Emily, Wolk, Alicja, Woods, Michael O., Wu, Anna H., Gruber, Stephen B., Brenner, Hermann, Peters, Ulrike, Chang-Claude, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008474/
https://www.ncbi.nlm.nih.gov/pubmed/29795306
http://dx.doi.org/10.1038/s41416-018-0108-8

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