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Eight-and-a-half syndrome: a rare potentially life-threatening disease
Purpose: To report a case of eight-and-a-half syndrome presenting with a conjugate horizontal gaze palsy, an ipsilateral internuclear ophthalmoplegia, and an ipsilateral lower motor neuron-like facial palsy. Methods: A 56-year-old male who came in for limitation of extraocular muscle motion – wherei...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008505/ https://www.ncbi.nlm.nih.gov/pubmed/29977730 http://dx.doi.org/10.3205/oc000086 |
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author | Mesina, Bryan Vincent Q. Sosuan, George Michael N. Reyes, Karen B. |
author_facet | Mesina, Bryan Vincent Q. Sosuan, George Michael N. Reyes, Karen B. |
author_sort | Mesina, Bryan Vincent Q. |
collection | PubMed |
description | Purpose: To report a case of eight-and-a-half syndrome presenting with a conjugate horizontal gaze palsy, an ipsilateral internuclear ophthalmoplegia, and an ipsilateral lower motor neuron-like facial palsy. Methods: A 56-year-old male who came in for limitation of extraocular muscle motion – wherein the only remaining movement is abduction of the left eye – and right-sided facial weakness. Magnetic resonance imaging revealed a well-defined lesion resembling a cavernoma, at the level of the ponto-medullary junction. Results: Eight-and-a-half syndrome results from a lesion affecting the paramedian pontine reticular formation, the median longitudinal fasciculus, and the facial nerve fascicle on one side. In this case, a cavernoma at the level of the ponto-medullary junction was compressing the important pontine structures. Conclusion: Although eight-and-a-half syndrome is most commonly caused by an infarction or demyelination, in rare instances, a space-occupying lesion at the level of the pons can be the etiology. It is of utmost importance to recognize the features of this disease entity to be able to exhaust the proper diagnostic exams, localize the lesion and determine the proper treatment regimen catered to each patient. |
format | Online Article Text |
id | pubmed-6008505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-60085052018-07-05 Eight-and-a-half syndrome: a rare potentially life-threatening disease Mesina, Bryan Vincent Q. Sosuan, George Michael N. Reyes, Karen B. GMS Ophthalmol Cases Article Purpose: To report a case of eight-and-a-half syndrome presenting with a conjugate horizontal gaze palsy, an ipsilateral internuclear ophthalmoplegia, and an ipsilateral lower motor neuron-like facial palsy. Methods: A 56-year-old male who came in for limitation of extraocular muscle motion – wherein the only remaining movement is abduction of the left eye – and right-sided facial weakness. Magnetic resonance imaging revealed a well-defined lesion resembling a cavernoma, at the level of the ponto-medullary junction. Results: Eight-and-a-half syndrome results from a lesion affecting the paramedian pontine reticular formation, the median longitudinal fasciculus, and the facial nerve fascicle on one side. In this case, a cavernoma at the level of the ponto-medullary junction was compressing the important pontine structures. Conclusion: Although eight-and-a-half syndrome is most commonly caused by an infarction or demyelination, in rare instances, a space-occupying lesion at the level of the pons can be the etiology. It is of utmost importance to recognize the features of this disease entity to be able to exhaust the proper diagnostic exams, localize the lesion and determine the proper treatment regimen catered to each patient. German Medical Science GMS Publishing House 2018-03-08 /pmc/articles/PMC6008505/ /pubmed/29977730 http://dx.doi.org/10.3205/oc000086 Text en Copyright © 2018 Mesina et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Mesina, Bryan Vincent Q. Sosuan, George Michael N. Reyes, Karen B. Eight-and-a-half syndrome: a rare potentially life-threatening disease |
title | Eight-and-a-half syndrome: a rare potentially life-threatening disease |
title_full | Eight-and-a-half syndrome: a rare potentially life-threatening disease |
title_fullStr | Eight-and-a-half syndrome: a rare potentially life-threatening disease |
title_full_unstemmed | Eight-and-a-half syndrome: a rare potentially life-threatening disease |
title_short | Eight-and-a-half syndrome: a rare potentially life-threatening disease |
title_sort | eight-and-a-half syndrome: a rare potentially life-threatening disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008505/ https://www.ncbi.nlm.nih.gov/pubmed/29977730 http://dx.doi.org/10.3205/oc000086 |
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