Cargando…

Eight-and-a-half syndrome: a rare potentially life-threatening disease

Purpose: To report a case of eight-and-a-half syndrome presenting with a conjugate horizontal gaze palsy, an ipsilateral internuclear ophthalmoplegia, and an ipsilateral lower motor neuron-like facial palsy. Methods: A 56-year-old male who came in for limitation of extraocular muscle motion – wherei...

Descripción completa

Detalles Bibliográficos
Autores principales: Mesina, Bryan Vincent Q., Sosuan, George Michael N., Reyes, Karen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008505/
https://www.ncbi.nlm.nih.gov/pubmed/29977730
http://dx.doi.org/10.3205/oc000086
_version_ 1783333189870157824
author Mesina, Bryan Vincent Q.
Sosuan, George Michael N.
Reyes, Karen B.
author_facet Mesina, Bryan Vincent Q.
Sosuan, George Michael N.
Reyes, Karen B.
author_sort Mesina, Bryan Vincent Q.
collection PubMed
description Purpose: To report a case of eight-and-a-half syndrome presenting with a conjugate horizontal gaze palsy, an ipsilateral internuclear ophthalmoplegia, and an ipsilateral lower motor neuron-like facial palsy. Methods: A 56-year-old male who came in for limitation of extraocular muscle motion – wherein the only remaining movement is abduction of the left eye – and right-sided facial weakness. Magnetic resonance imaging revealed a well-defined lesion resembling a cavernoma, at the level of the ponto-medullary junction. Results: Eight-and-a-half syndrome results from a lesion affecting the paramedian pontine reticular formation, the median longitudinal fasciculus, and the facial nerve fascicle on one side. In this case, a cavernoma at the level of the ponto-medullary junction was compressing the important pontine structures. Conclusion: Although eight-and-a-half syndrome is most commonly caused by an infarction or demyelination, in rare instances, a space-occupying lesion at the level of the pons can be the etiology. It is of utmost importance to recognize the features of this disease entity to be able to exhaust the proper diagnostic exams, localize the lesion and determine the proper treatment regimen catered to each patient.
format Online
Article
Text
id pubmed-6008505
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher German Medical Science GMS Publishing House
record_format MEDLINE/PubMed
spelling pubmed-60085052018-07-05 Eight-and-a-half syndrome: a rare potentially life-threatening disease Mesina, Bryan Vincent Q. Sosuan, George Michael N. Reyes, Karen B. GMS Ophthalmol Cases Article Purpose: To report a case of eight-and-a-half syndrome presenting with a conjugate horizontal gaze palsy, an ipsilateral internuclear ophthalmoplegia, and an ipsilateral lower motor neuron-like facial palsy. Methods: A 56-year-old male who came in for limitation of extraocular muscle motion – wherein the only remaining movement is abduction of the left eye – and right-sided facial weakness. Magnetic resonance imaging revealed a well-defined lesion resembling a cavernoma, at the level of the ponto-medullary junction. Results: Eight-and-a-half syndrome results from a lesion affecting the paramedian pontine reticular formation, the median longitudinal fasciculus, and the facial nerve fascicle on one side. In this case, a cavernoma at the level of the ponto-medullary junction was compressing the important pontine structures. Conclusion: Although eight-and-a-half syndrome is most commonly caused by an infarction or demyelination, in rare instances, a space-occupying lesion at the level of the pons can be the etiology. It is of utmost importance to recognize the features of this disease entity to be able to exhaust the proper diagnostic exams, localize the lesion and determine the proper treatment regimen catered to each patient. German Medical Science GMS Publishing House 2018-03-08 /pmc/articles/PMC6008505/ /pubmed/29977730 http://dx.doi.org/10.3205/oc000086 Text en Copyright © 2018 Mesina et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Mesina, Bryan Vincent Q.
Sosuan, George Michael N.
Reyes, Karen B.
Eight-and-a-half syndrome: a rare potentially life-threatening disease
title Eight-and-a-half syndrome: a rare potentially life-threatening disease
title_full Eight-and-a-half syndrome: a rare potentially life-threatening disease
title_fullStr Eight-and-a-half syndrome: a rare potentially life-threatening disease
title_full_unstemmed Eight-and-a-half syndrome: a rare potentially life-threatening disease
title_short Eight-and-a-half syndrome: a rare potentially life-threatening disease
title_sort eight-and-a-half syndrome: a rare potentially life-threatening disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008505/
https://www.ncbi.nlm.nih.gov/pubmed/29977730
http://dx.doi.org/10.3205/oc000086
work_keys_str_mv AT mesinabryanvincentq eightandahalfsyndromeararepotentiallylifethreateningdisease
AT sosuangeorgemichaeln eightandahalfsyndromeararepotentiallylifethreateningdisease
AT reyeskarenb eightandahalfsyndromeararepotentiallylifethreateningdisease