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Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase

The ATP-powered protein degradation machinery plays essential roles in maintaining protein homeostasis in all organisms. Robust proteolytic activities are typically sequestered within protein complexes to avoid the fatal removal of essential proteins. Because the openings of proteolytic chambers are...

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Detalles Bibliográficos
Autores principales: Esaki, Masatoshi, Johjima-Murata, Ai, Islam, Md. Tanvir, Ogura, Teru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008533/
https://www.ncbi.nlm.nih.gov/pubmed/29951484
http://dx.doi.org/10.3389/fmolb.2018.00056