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Different Expression Levels of Human Mutant Ubiquitin B(+1) (UBB(+1)) Can Modify Chronological Lifespan or Stress Resistance of Saccharomyces cerevisiae

The ubiquitin-proteasome system (UPS) is the main pathway responsible for the degradation of misfolded proteins, and its dysregulation has been implicated in several neurodegenerative diseases, including Alzheimer’s disease (AD). UBB(+1), a mutant variant of ubiquitin B, was found to accumulate in n...

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Detalles Bibliográficos
Autores principales:	Muñoz-Arellano, Ana Joyce, Chen, Xin, Molt, Andrea, Meza, Eugenio, Petranovic, Dina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008557/ https://www.ncbi.nlm.nih.gov/pubmed/29950972 http://dx.doi.org/10.3389/fnmol.2018.00200

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