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Andrographolide Inhibits Mechanical and Thermal Hyperalgesia in a Rat Model of HIV-Induced Neuropathic Pain
Aim: In this study, we investigated whether andrographolide (Andro) can alleviate neuropathic pain induced by HIV gp120 plus ddC treatment and the mechanism of its action. Methods: The paw withdrawal threshold and the paw withdrawal latency were observed to assess pain behaviors in all groups of the...
Autores principales: | Yi, Zhihua, Ouyang, Shuai, Zhou, Congfa, Xie, Lihui, Fang, Zhi, Yuan, Huilong, Yang, Jinpu, Zou, Lifang, Jia, Tianyu, Zhao, Shanhong, Li, Lin, Shi, Liran, Gao, Yun, Li, Guilin, Liu, Shuangmei, Xu, Hong, Xu, Changshui, Zhang, Chunping, Liang, Shangdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008568/ https://www.ncbi.nlm.nih.gov/pubmed/29950989 http://dx.doi.org/10.3389/fphar.2018.00593 |
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